Kaohsiung Medical University, Taiwan.
Kaohsiung Municipal Hsiao-Kang Hospital, Taiwan.
Int J Psychiatry Med. 2013;46(1):39-55. doi: 10.2190/PM.46.1.d.
Depression, anxiety, and irritability are the three most studied symptoms of premenstrual dysphoric disorder (PMDD). This study aimed to assess the premenstrual exacerbation of these symptoms and their role in the diagnosis or functional impairment of PMDD.
We recruited women with PMDD not undergoing any treatment and control subjects from the community. The diagnosis of PMDD was based on a positive score on the Premenstrual Symptoms Screening Tool and confirmed by psychiatric interviews and questionnaire follow-up for three menstrual cycles. A total of 67 women with PMDD and 75 control subjects participated the survey and reach the final analysis. They complete the Center for Epidemiological Studies, the Chinese Version of the Buss-Durkee Hostility Inventory-Short Form, and the Penn State Worry Questionnaire in both the premenstrual and follicular phases.
Women with PMDD, but no controls, demonstrate the premenstrual exacerbation of these three symptoms. Depression was the most prominent feature of the PMDD diagnosis while irritability was most frequently associated with functional impairment.
Depression and irritability should be properly evaluated and treated among women with PMDD.
抑郁、焦虑和易怒是经前期烦躁障碍（PMDD）中研究最多的三个症状。本研究旨在评估这些症状的经前期加重情况及其在 PMDD 诊断或功能障碍中的作用。
我们招募了未经任何治疗的 PMDD 女性患者和社区中的对照组女性。PMDD 的诊断基于经前期症状筛查工具的阳性评分，并通过精神病学访谈和问卷调查随访三个月经周期进行确认。共有 67 名 PMDD 女性患者和 75 名对照组女性参与了调查并进行了最终分析。她们在经前期和卵泡期完成了流行病学研究中心抑郁量表、中文版 Buss-Durkee 敌意量表短式和宾夕法尼亚州忧虑问卷。
PMDD 女性患者出现这些症状的经前期加重，而对照组女性则没有。抑郁是 PMDD 诊断中最突出的特征，而易怒与功能障碍最相关。
PMDD 女性应适当评估和治疗抑郁和易怒。
