经前期烦躁障碍女性的失眠、注意力不集中和疲劳症状。
Insomnia, Inattention and Fatigue Symptoms of Women with Premenstrual Dysphoric Disorder.
机构信息
Department of Psychiatry, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung Medical University, Kaohsiung 801, Taiwan.
Department of Psychiatry, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
出版信息
Int J Environ Res Public Health. 2021 Jun 8;18(12):6192. doi: 10.3390/ijerph18126192.
AIM
Premenstrual dysphoric disorder (PMDD) has predictable, cyclic, psychological, and somatic symptoms, such as sleep problems. They result in functional impairment, are aggravated in the late luteal phase of the menstrual cycle, and are resolved by menstruation. The present study evaluated the insomnia, inattention, and fatigue symptoms of PMDD and their fluctuations during the menstrual cycle.
METHODS
A total of 100 women were diagnosed as having PMDD based on psychiatric interviews and a prospective investigation of three menstrual cycles. A total of 96 individuals without PMDD were recruited as controls. Their symptoms, namely insomnia, inattention, and fatigue as well as functional impairment were assessed by using the premenstrual symptoms screening tool, the Pittsburgh insomnia rating scale, the attention and performance self-assessment scale, and the fatigue-assessment scale during both premenstrual and follicular phases.
RESULTS
In both the premenstrual and follicular phases, women with PMDD experienced more severe insomnia, inattentiveness, and fatigue than did women in the control group. A paired -test demonstrated that women with PMDD had more severe severity insomnia, inattentiveness, and fatigue in the luteal phase than in the follicular phase. A repeated-measures analysis of variance demonstrated that the interaction period of PMDD and a menstrual cycle was significantly associated with insomnia, inattentiveness, and fatigue. A further correlation analysis demonstrated that all three symptoms were positively associated with self-reported functional impairment due to PMDD.
CONCLUSIONS
Our results demonstrated that women with PMDD experienced an exacerbation of insomnia, memory problems, difficulty maintaining focus, and fatigue in the premenstrual phase. These symptoms are correlated with PMDD symptoms severity and functional impairment, and as such, they should be evaluated, and interventions should be employed in the late luteal phase of women with PMDD.
目的
经前期烦躁障碍（PMDD）具有可预测的、周期性的心理和躯体症状，如睡眠问题。这些症状导致功能障碍，在月经周期的黄体晚期加重，并在月经期间缓解。本研究评估了 PMDD 的失眠、注意力不集中和疲劳症状及其在月经周期中的波动。
方法
共 100 名女性根据精神病学访谈和对三个月经周期的前瞻性调查被诊断为 PMDD。共招募了 96 名无 PMDD 的个体作为对照组。使用经前期症状筛查工具、匹兹堡睡眠质量指数、注意力和表现自我评估量表以及疲劳评估量表，在经前期和卵泡期评估他们的症状，包括失眠、注意力不集中和疲劳以及功能障碍。
结果
在经前期和卵泡期，PMDD 女性的失眠、注意力不集中和疲劳比对照组女性更严重。配对 t 检验表明，PMDD 女性在黄体期的严重失眠、注意力不集中和疲劳比卵泡期更严重。重复测量方差分析表明，PMDD 和月经周期的交互作用期与失眠、注意力不集中和疲劳显著相关。进一步的相关分析表明，所有三种症状都与 PMDD 引起的自我报告功能障碍呈正相关。
结论
我们的研究结果表明，PMDD 女性在经前期会出现失眠、记忆力问题、难以集中注意力和疲劳加重的情况。这些症状与 PMDD 症状严重程度和功能障碍相关，因此应在 PMDD 女性的黄体晚期进行评估和干预。
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