一种来自北沙参的新芳香糖苷。

A new aromatic glycoside from Glehnia littoralis.

作者信息

Feng Zi-Jin, Zhang Xiao-Hong, Zhang Jian-Peng, Shang Xiao-Hui, Gao Yun, Lu Xiao-Ling, Liu Xiao-Yu, Jiao Bing-Hua

机构信息

a Department of Biochemistry and Molecular Biology , College of Basic Medical Sciences, Second Military Medical University , Xiangyin Road 800, Shanghai , P.R. China.

出版信息

Nat Prod Res. 2014;28(8):551-4. doi: 10.1080/14786419.2014.886206. Epub 2014 Feb 18.

DOI:10.1080/14786419.2014.886206

PMID:24547738

Abstract

A new aromatic glycoside (1) was isolated from the roots of Glehnia littoralis Fr. Schmidtex Miq. Its structure was elucidated as vanillic acid 1-O-[β-D-apiofuranosyl-(1 → 6)-β-D-glucopyranoside] ester mainly by analysing the NMR and MS spectral data. In the in vitro assays, compound 1 displayed some TNF-α secretion inhibitory activity.

摘要

从珊瑚菜（Glehnia littoralis Fr. Schmidtex Miq.）的根中分离出一种新的芳香糖苷（1）。通过分析核磁共振（NMR）和质谱（MS）光谱数据，其结构被确认为香草酸1 - O - [β - D - 阿糖呋喃糖基 -（1→6）-β - D - 吡喃葡萄糖苷]酯。在体外试验中，化合物1表现出一定的肿瘤坏死因子 -α（TNF-α）分泌抑制活性。