掌叶大黄根中的两种新蒽醌苷。

Two new anthraquinone glycosides from the roots of Rheum palmatum.

作者信息

Zhang Cun, Li Li, Xiao Yong-Qing, Tian Guo-Fang, Chen Dong-Dong, Wang Yun, Li Yu-Tian, Huang Wen-Qian

机构信息

Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.

出版信息

J Asian Nat Prod Res. 2010 Dec;12(12):1026-32. doi: 10.1080/10286020.2010.529612.

DOI:10.1080/10286020.2010.529612

PMID:21128142

Abstract

Two new anthraquinone glycosides, named 1-methyl-8-hydroxyl-9,10-anthraquinone-3-O-β-D-(6'-O-cinnamoyl)glucopyranoside (1) and rhein-8-O-β-D-[6'-O-(3''-methoxyl malonyl)]glucopyranoside (2), have been isolated from the roots of Rheum palmatum, together with seven known compounds, rhein-8-O-β-D-glucopyranoside (3), physcion-8-O-β-D-glucopyranoside (4), chrysophanol-8-O-β-D-glucopyranoside (5), aleo-emodin-8-O-β-D-glucopyranoside (6), emodin-8-O-β-D-glucopyranoside (7), aleo-emodin-ω-O-β-D-glucopyranoside (8), and emodin-1-O-β-D-glucopyranoside (9). Their structures were elucidated on the basis of chemical and spectral analysis.

摘要

从掌叶大黄的根部分离出了两种新的蒽醌苷，分别命名为1-甲基-8-羟基-9,10-蒽醌-3-O-β-D-(6'-O-肉桂酰基)吡喃葡萄糖苷（1）和大黄酸-8-O-β-D-[6'-O-(3''-甲氧基丙二酰基)]吡喃葡萄糖苷（2），同时还分离出了七种已知化合物，大黄酸-8-O-β-D-吡喃葡萄糖苷（3）、大黄素甲醚-8-O-β-D-吡喃葡萄糖苷（4）、大黄酚-8-O-β-D-吡喃葡萄糖苷（5）、芦荟大黄素-8-O-β-D-吡喃葡萄糖苷（6）、大黄素-8-O-β-D-吡喃葡萄糖苷（7）、芦荟大黄素-ω-O-β-D-吡喃葡萄糖苷（8）和大黄素-1-O-β-D-吡喃葡萄糖苷（9）。通过化学和光谱分析确定了它们的结构。