Riemann J F, de Mas R, Ginsbach C, Harloff M, Kohler B
Medizinische Klinik C, Klinikum der Stadt Ludwigshafen am Rhein.
Dtsch Med Wochenschr. 1988 Jul 1;113(26):1057-60. doi: 10.1055/s-2008-1067766.
During a 20 months period (1. 10. 1985-31. 5. 1987) 20 patients with advanced rectal carcinoma received palliative treatment by laser (Neodymium-YAG), 18 for subtotal rectal stenosis, two for profuse bleeding from an exophytic tumour. Re-establishment of intestinal passage or stoppage of bleeding was achieved in all patients, after a mean of 3.4 (1-5) applications. The treatment was well tolerated, cured the anaemia, removed the obstruction and ended painful stool evacuation. To-date 11 patients have died, seven of the malignant tumour. Nine patients are still alive. The mean survival time for all 20 patients is 5.3 months so far, similar to that after a palliative colostomy. There were no complications.
在1985年10月1日至1987年5月31日的20个月期间，20例晚期直肠癌患者接受了激光（钕钇铝石榴石）姑息治疗，其中18例因直肠大部狭窄，2例因外生性肿瘤大量出血。平均经过3.4次（1 - 5次）治疗后，所有患者的肠道通路得以重建或出血停止。该治疗耐受性良好，治愈了贫血，解除了梗阻，结束了痛苦的排便过程。迄今为止，11例患者已死亡，其中7例死于恶性肿瘤。9例患者仍存活。到目前为止，所有20例患者的平均生存时间为5.3个月，与姑息性结肠造口术后的生存时间相似。未出现并发症。
