Labenz J, Börsch G
Med Klin (Munich). 1989 Oct 15;84(10):479-82.
In the years 1985 to 1988, 15 patients with advanced rectal or rectosigmoidal tumors causing stenosis or bleeding were submitted to palliative Neodymium-YAG laser therapy. In addition, twelve patients with remnant adenomas after endoscopic polypectomy and three patients with benign strictures were treated to attempt cure. Stenosis and bleeding could be effectively treated in all cases. Three patients developed unmanageable tumor recurrences and eventually had to undergo colostomy after a mean lag period of seven months (1.6 to 8.8 months). Mean survival time presently is 6.3 months. Of the tumor patients, five are still alive. Ten out of twelve remnant colorectal adenomas could be eradicated by additional laser treatment. There was one recurrence. Two patients did not attend to follow-ups. All three anastomotic strictures could be recanalized by laser treatment. Two of these three patients later developed recurrences, which could likewise be effectively managed by repeated laser application. There were no treatment-associated complications in these patients. Our results give additional confirmation, that ND-YAG lasers are effective for the palliative treatment of tumor stenoses and tumor bleeding of the rectal and rectosigmoidal area and also may be a valuable therapeutic modality for benign strictures and remnant adenomas in selected patients.
1985年至1988年间,15例因晚期直肠或直肠乙状结肠肿瘤导致狭窄或出血的患者接受了姑息性钕钇铝石榴石激光治疗。此外,对12例内镜下息肉切除术后残留腺瘤患者和3例良性狭窄患者进行了治疗以尝试治愈。所有病例的狭窄和出血均得到有效治疗。3例患者出现无法控制的肿瘤复发,平均延迟7个月(1.6至8.8个月)后最终不得不接受结肠造口术。目前的平均生存时间为6.3个月。肿瘤患者中有5例仍然存活。12例残留大肠腺瘤中有10例可通过额外的激光治疗根除。有1例复发。2例患者未进行随访。所有3例吻合口狭窄均可通过激光治疗再通。这3例患者中有2例后来出现复发,同样可通过重复激光治疗有效控制。这些患者中没有与治疗相关的并发症。我们的结果进一步证实,钕钇铝石榴石激光对直肠和直肠乙状结肠区域的肿瘤狭窄和肿瘤出血的姑息治疗有效,对于某些患者的良性狭窄和残留腺瘤也可能是一种有价值的治疗方式。