Berent Allyson C, Weisse Chick W, Todd Kimberly, Bagley Demetrius H
Department of Diagnostic Imaging and Interventional Radiology, The Animal Medical Center, 510 E 62nd St, New York, NY 10065.
J Am Vet Med Assoc. 2014 Mar 1;244(5):559-76. doi: 10.2460/javma.244.5.559.
OBJECTIVE--To evaluate the technical, short-term, and long-term outcomes in cats with benign ureteral obstructions treated by means of double-pigtail ureteral stent placement. DESIGN--Retrospective case series. ANIMALS--69 cats (79 ureters). PROCEDURES--The diagnosis of benign ureteral obstruction was made via abdominal ultrasonography, radiography, and ureteropyelography. Ureteral stent placement was attempted endoscopically, surgically, or both, with fluoroscopic guidance. The medical records were reviewed for pre-, intra-, and postoperative data; complications; and outcome. RESULTS--69 cats (79 ureters) had stent placement attempted for various causes: ureterolithiasis (56/79 [71%]), stricture (10/79 [13%]), both ureterolithiasis and stricture (12/79 [15%]), or a purulent plug (1/79 [1%]). Stent placement was successful in 75 of 79 ureters (95%). Median number of stones per ureter was 4 (range, 0 to > 50), and 67 of 79 (85%) had concurrent nephrolithiasis. Preoperative azotemia was present in 95% (66/69) of cats (median creatinine concentration, 5.3 mg/dL [range, 1.1 to 25.8 mg/dL]), and 71% (49/69) remained azotemic (median, 2.1 mg/dL [range, 1.0 to 11.8 mg/dL]) after successful surgery. Procedure-related, postoperative (< 7 days), short-term (7 to 30 days), and long-term (> 30 days) complications occurred in 8.7% (6/69; 7/79 ureters), 9.1% (6/66), 9.8% (6/61), and 33% (20/60) of cats, respectively; most of these complications were minor and associated with intermittent dysuria or the need for ureteral stent exchange. The perioperative mortality rate was 7.5% (5/69), and no deaths were procedure related. The median survival time was 498 days (range, 2 to > 1,278 days). For patients with a renal cause of death, median survival time was > 1,262 days, with only 14 of 66 cats (21%) dying of chronic kidney disease. Nineteen (27%) cats needed a stent exchange (stricture in-growth [n = 10], migration [4], ureteritis [2], dysuria [2], pyelonephritis [1], or reflux [1]). No patient died of the procedure or recurrent ureteral obstruction. CONCLUSIONS AND CLINICAL RELEVANCE--Results of the present study indicated that ureteral stenting is an effective treatment for benign ureteral obstructions in cats regardless of obstructive location, cause, or stone number. The perioperative morbidity and mortality rates were lower than those reported with traditional ureteral surgery. The short- and long-term complications were typically minor but may necessitate stent exchange or use of an alternative device, particularly with ureteral strictures. The prognosis for feline ureteral obstructions after ureteral stenting could be considered good when the procedure is performed by trained specialists.
目的——评估采用双猪尾输尿管支架置入术治疗猫良性输尿管梗阻的技术、短期和长期疗效。
设计——回顾性病例系列研究。
动物——69只猫(79条输尿管)。
方法——通过腹部超声、X线摄影和输尿管肾盂造影诊断良性输尿管梗阻。在荧光镜引导下,尝试通过内镜、手术或两者结合的方式置入输尿管支架。回顾病历以获取术前、术中和术后数据、并发症及预后情况。
结果——69只猫(79条输尿管)因各种原因尝试置入支架:输尿管结石(56/79 [71%])、狭窄(10/79 [13%])、输尿管结石合并狭窄(12/79 [15%])或脓性栓子(1/79 [1%])。79条输尿管中有75条(95%)成功置入支架。每条输尿管结石的中位数为4(范围为0至>50),79条中有67条(85%)同时患有肾结石。95%(66/69)的猫术前存在氮质血症(肌酐浓度中位数为5.3 mg/dL [范围为1.1至25.8 mg/dL]),成功手术后71%(49/69)仍存在氮质血症(中位数为2.1 mg/dL [范围为1.0至11.8 mg/dL])。与手术相关的术后(<7天)、短期(7至30天)和长期(>30天)并发症分别发生在8.7%(6/69;7/79条输尿管)、9.1%(6/66)、9.8%(6/61)和33%(20/60)的猫中;这些并发症大多较轻微,与间歇性排尿困难或输尿管支架更换需求有关。围手术期死亡率为7.5%(5/69),且无死亡与手术相关。中位生存时间为498天(范围为2至>1278天)。对于因肾脏原因死亡的患者,中位生存时间>1262天,66只猫中只有14只(21%)死于慢性肾病。19只(27%)猫需要更换支架(狭窄内生长[n = 10]、移位[4]、输尿管炎[2]、排尿困难[2]、肾盂肾炎[1]或反流[1])。无患者死于手术或复发性输尿管梗阻。
结论及临床意义——本研究结果表明,无论梗阻部位、原因或结石数量如何,输尿管支架置入术都是治疗猫良性输尿管梗阻的有效方法。围手术期发病率和死亡率低于传统输尿管手术报道的水平。短期和长期并发症通常较轻微,但可能需要更换支架或使用替代装置,尤其是对于输尿管狭窄。当由训练有素的专家进行该手术时,猫输尿管梗阻经输尿管支架置入术后的预后可被认为良好。