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皮下输尿管旁路装置用于治疗猫良性输尿管梗阻:2009年至2015年134只猫的174条输尿管

Use of a subcutaneous ureteral bypass device for treatment of benign ureteral obstruction in cats: 174 ureters in 134 cats (2009-2015).

作者信息

Berent Allyson C, Weisse Chick W, Bagley Demetrius H, Lamb Kenneth

出版信息

J Am Vet Med Assoc. 2018 Nov 15;253(10):1309-1327. doi: 10.2460/javma.253.10.1309.

Abstract

OBJECTIVE To determine outcomes of subcutaneous ureteral bypass (SUB) device placement for treatment of benign ureteral obstruction in cats. DESIGN Retrospective case series. ANIMALS 134 cats with SUB devices placed in 174 obstructed ureters during 144 hospitalizations. PROCEDURES Medical records of cats that underwent SUB device placement for treatment of benign ureteral obstruction between 2009 and 2015 were reviewed. The SUB device was placed by use of fluoroscopic and surgical methods. Signalment, history, diagnostic imaging results, postprocedural results, duration of hospitalization, complications, and short- and long-term outcomes were recorded. RESULTS Ureteral obstructions were caused by ureterolithiasis (114/174 [65.5%]), stricture (28/174 [16.1%]), both ureterolithiasis and stricture (29/174 [16.7%]), or pyonephrosis (1/174 [0.6%]); in 2 (1.1%) cats, the cause was not recorded. Fifty-two of the 134 (39%) cats had bilateral ureteral obstruction. At admission, 127 (95%) cats were azotemic. Median serum creatinine concentrations at admission and 3 months after SUB device placement were 6.6 and 2.6 mg/dL, respectively. Median renal pelvis diameters before and after the procedure were 9.2 and 1.5 mm, respectively. Postsurgical complications included device occlusion with blood clots (14/172 [8.1%]), device leakage (6/172 [3.5%]), and kinking of the device tubing (8/174 [4.6%]). Cats survived to hospital discharge after 135 of the 144 (94%) hospital admissions. The most common long-term complication was catheter mineralization (40/165 [24.2%]), which was documented a median of 463 days after device placement. A high postoperative serum ionized calcium concentration was significantly associated with SUB device occlusion. CONCLUSIONS AND CLINICAL RELEVANCE Results suggested that SUB device placement may be a viable option for treatment of cats with benign ureteral obstruction.

摘要

目的 确定皮下输尿管旁路(SUB)装置置入术治疗猫良性输尿管梗阻的效果。 设计 回顾性病例系列研究。 动物 144 次住院期间,134 只猫的 174 条梗阻输尿管置入了 SUB 装置。 方法 回顾 2009 年至 2015 年间接受 SUB 装置置入术治疗良性输尿管梗阻的猫的病历。SUB 装置通过荧光镜和手术方法置入。记录动物的信号、病史、诊断性影像学检查结果、术后结果、住院时间、并发症以及短期和长期结局。 结果 输尿管梗阻的原因包括输尿管结石(114/174 [65.5%])、狭窄(28/174 [16.1%])、输尿管结石合并狭窄(29/174 [16.7%])或肾盂积脓(1/174 [0.6%]);2 只(1.1%)猫的病因未记录。134 只猫中有 52 只(39%)存在双侧输尿管梗阻。入院时,127 只(95%)猫存在氮质血症。入院时和 SUB 装置置入后 3 个月时血清肌酐浓度中位数分别为 6.6 和 2.6 mg/dL。术前和术后肾盂直径中位数分别为 9.2 和 1.5 mm。术后并发症包括装置被血凝块阻塞(14/172 [8.1%])、装置渗漏(6/172 [3.5%])和装置管道扭结(8/174 [4.6%])。144 次住院中有 135 次(94%)猫存活至出院。最常见的长期并发症是导管矿化(40/165 [24.2%]),装置置入后记录到矿化的中位数时间为 463 天。术后血清离子钙浓度升高与 SUB 装置阻塞显著相关。 结论及临床意义 结果表明,SUB 装置置入术可能是治疗猫良性输尿管梗阻的一种可行选择。

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