Yagerman Sarah E, Chen Lucy, Jaimes Natalia, Dusza Stephen W, Halpern Allan C, Marghoob Ashfaq
Weill Cornell Medical College, New York, USA.
Australas J Dermatol. 2014 May;55(2):119-24. doi: 10.1111/ajd.12143. Epub 2014 Feb 19.
BACKGROUND/OBJECTIVES: Many melanomas are of a diameter smaller than 6 mm and may lack classical asymmetry, border irregularity and colour variegation (ABCD). The objectives of this article are to characterise the fidelity of melanomas diagnosed in a high-risk clinic to the ABCD and to review potential methods for early clinical detection of melanoma.
All cases of primary melanoma diagnosed by one clinician at the Memorial Sloan-Kettering Cancer Center over the past 11 years were evaluated for the presence of the ABCD. The melanomas were analysed for asymmetry of contour, unevenness in distribution of colours and textures, border irregularity, number of colours present and diameter.
In all, 236 melanomas were analysed. Of these, asymmetry of contour was present in 65% and 94% demonstrated unevenness in the distribution of colours and textures. The borders were regular in 12% of the melanomas and colour variegation was present in 63%. In total, 28% of the lesions were small, with a diameter less than 6 mm. This study was limited by the subjectivity of clinical lesion analysis.
We put forward for your consideration a new mnemonic: 'Do UC (different, uneven, changing) the melanoma?' This mnemonic encompasses differential, analytical and comparative cognition strategies for an enhanced early detection of melanoma.
背景/目的:许多黑色素瘤直径小于6毫米,可能缺乏典型的不对称性、边界不规则和颜色斑驳(ABCD特征)。本文的目的是描述在高危诊所诊断出的黑色素瘤符合ABCD特征的情况,并综述黑色素瘤早期临床检测的潜在方法。
对纪念斯隆凯特琳癌症中心一名临床医生在过去11年中诊断出的所有原发性黑色素瘤病例进行ABCD特征评估。分析黑色素瘤的轮廓不对称性、颜色和纹理分布不均匀性、边界不规则性、存在的颜色数量和直径。
共分析了236例黑色素瘤。其中,65%存在轮廓不对称,94%表现出颜色和纹理分布不均匀。12%的黑色素瘤边界规则,63%存在颜色斑驳。总共28%的病变较小,直径小于6毫米。本研究受临床病变分析主观性的限制。
我们提出一个新的助记符供您考虑:“你能识别(不同、不均匀、变化)黑色素瘤吗?”这个助记符包含了鉴别、分析和比较认知策略,以加强黑色素瘤的早期检测。