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对36只猫的药物治疗无效的慢性角膜溃疡进行浅表角膜切除术。

Superficial keratectomy for chronic corneal ulcers refractory to medical treatment in 36 cats.

作者信息

Jégou Jean-Pierre, Tromeur Florence

机构信息

Veterinary Eye Clinic, 39 rue Rouelle, 75015, Paris, France.

Vetoadom, 140 avenue Henri Ginoux, 92120, Montrouge, France.

出版信息

Vet Ophthalmol. 2015 Jul;18(4):335-40. doi: 10.1111/vop.12153. Epub 2014 Feb 18.

DOI:10.1111/vop.12153
PMID:24548614
Abstract

OBJECTIVE

To review the outcome of a case series in which superficial keratectomy was used as a treatment for chronic corneal ulceration.

STUDY DESIGN

Retrospective study

ANIMALS STUDIED

Thirty-six cats (41 eyes) with ulcerative keratitis.

RESULTS

Forty-one superficial lamellar keratectomies were performed. Thirty-two and a half percent (32.5%) of the ulcers were resolved within 2 weeks and 85% within 4 weeks after surgery. Nonhealing surgical cases after 4 weeks (13% of the eyes) resolved with prolonged postoperative medical treatment. The mean time to healing was 22.1 days (range 7-74 days). At the end of the follow-up period (mean 8.9 months, range 1-36 months), 82.5% of eyes had regained very good to excellent corneal transparency. Nine cases relapsed (21.9% of the eyes) after surgery. Of those cases, the cornea of eight cats healed after undergoing medical treatment, and one underwent a second limited superficial lamellar keratectomy.

CONCLUSION

Superficial keratectomy in cats is an effective treatment to resolve chronic ulcerative keratitis refractory to medical treatment.

摘要

目的

回顾一系列使用浅层角膜切除术治疗慢性角膜溃疡病例的结果。

研究设计

回顾性研究

研究动物

36只患有溃疡性角膜炎的猫(41只眼)

结果

共进行了41次浅层板层角膜切除术。术后2周内32.5%的溃疡愈合,4周内85%愈合。术后4周仍未愈合的手术病例(占眼数的13%)经延长术后药物治疗后愈合。平均愈合时间为22.1天(范围7 - 74天)。在随访期末(平均8.9个月,范围1 - 36个月),82.5%的眼恢复了非常好至极佳的角膜透明度。9例术后复发(占眼数的21.9%)。其中,8只猫的角膜经药物治疗后愈合,1只猫接受了第二次有限的浅层板层角膜切除术。

结论

猫的浅层角膜切除术是治疗药物治疗无效的慢性溃疡性角膜炎的有效方法。

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