La Croix N C, van der Woerdt A, Olivero D K
Bobst Hospital of the Animal Medical Center, New York, NY 10021, USA.
J Am Vet Med Assoc. 2001 Mar 1;218(5):733-5. doi: 10.2460/javma.2001.218.733.
To compare mean healing times after debridement, debridement with grid keratotomy, and superficial keratectomy in cats with nonhealing corneal ulcers.
Retrospective study.
29 cats with 36 nonhealing corneal ulcers.
Medical records of cats with nonhealing corneal ulcers were reviewed. Signalment, duration of clinical signs, ophthalmic abnormalities, and response to various treatment protocols were recorded.
Mean age of affected cats was 7 years, 8 months. Affected breeds included domestic shorthair (17 cats), Persian (9), Himalayan (2), and Siamese (1). Clinical signs were evident for approximately 2 weeks prior to referral. Both eyes were affected in 4 cats. Mean healing time of ulcers treated with superficial debridement was 30 days. Mean healing time of ulcers treated with superficial debridement and grid keratotomy was 42 days. Superficial keratectomy was performed on 2 eyes and resulted in a healing time of 2 weeks. Formation of a corneal sequestrum was evident in 2 of 21 eyes treated with superficial debridement. Formation of a corneal sequestrum was evident in 4 of 13 eyes treated with superficial debridement and grid keratotomy.
Brachycephalic cats appear to be predisposed to developing nonhealing corneal ulcers. The combination of superficial debridement and grid keratotomy did not decrease mean healing time of nonhealing ulcers, compared with superficial debridement alone. Grid keratotomy may predispose cats with corneal ulcers to develop a corneal sequestrum.
比较清创术、清创联合网格状角膜切开术以及浅表角膜切除术治疗猫非愈合性角膜溃疡后的平均愈合时间。
回顾性研究。
29只患有36处非愈合性角膜溃疡的猫。
回顾患有非愈合性角膜溃疡猫的病历。记录品种、临床症状持续时间、眼科异常情况以及对各种治疗方案的反应。
患猫的平均年龄为7岁8个月。患猫品种包括家猫（17只）、波斯猫（9只）、喜马拉雅猫（2只）和暹罗猫（1只）。转诊前临床症状已出现约2周。4只猫双眼患病。浅表清创术治疗的溃疡平均愈合时间为30天。浅表清创联合网格状角膜切开术治疗的溃疡平均愈合时间为42天。对2只眼实施了浅表角膜切除术，愈合时间为2周。浅表清创术治疗的21只眼中有2只出现角膜腐骨形成。浅表清创联合网格状角膜切开术治疗的13只眼中有4只出现角膜腐骨形成。
短头品种猫似乎易患非愈合性角膜溃疡。与单纯浅表清创术相比，浅表清创联合网格状角膜切开术并未缩短非愈合性溃疡的平均愈合时间。网格状角膜切开术可能使患角膜溃疡的猫易形成角膜腐骨。
