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20 岁健康女性股骨干骨折髓内钉固定术后 Purtscher 视网膜病变——1 例罕见病例报告及文献复习

Purtscher's retinopathy after intramedullary nailing of a femoral shaft fracture in a 20-year old healthy female - report of a rare case and review of the literature.

机构信息

University Clinic for Trauma Surgery and Sports Injuries, Müllner Hauptstraße 48, Salzburg A-5020, Austria.

出版信息

BMC Musculoskelet Disord. 2014 Feb 19;15:42. doi: 10.1186/1471-2474-15-42.

DOI:10.1186/1471-2474-15-42
PMID:24548655
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3936909/
Abstract

BACKGROUND

Purtscher's retinopathy is a sight threatening, occlusive microvasculopathy associated with trauma, it is rarely reported after long bone fractures.

CASE PRESENTATION

A 20-year-old female sustained a femoral shaft fracture (AO 32-A2.3) in a ski accident colliding with a snowgun and was treated with intramedullary nailing one hour after the accident. 14 hours after surgery the patient complained of loss of vision in both eyes and was therefore referred to a neurologist, furthermore an MRI scan of the brain was performed. Neither showed any pathological findings. The patient was finally transferred to an ophthalmology department. After slit lamp examination and funduscopy Purtscher's retinopathy was diagnosed. Treatment was started right after diagnosis and 5 days after the onset of symptoms. The patient was administered intravenous haemo-rheologic therapy for five days as well as low molecular heparine in therapeutic dose and Vasonit® 400 mg bid orally.At follow-up 4 weeks and 6 months later visual acuity had improved after 4 weeks before that exam. At final follow-up the symptoms had almost resolved completely and uncorrected visual acuity (UCVA) and best corrected visual acuity had improved from originally 0.25 decimal in both eyes to 0.8 decimal UCVA and BCVA in both eyes.

CONCLUSIONS

Patients suffering from perioperative loss of vision have to be referred for ophthalmological and neurological assessment as soon as possible. History of trauma and visual loss can point to the diagnosis of Purtscher's retinopathy.

摘要

背景

Purtscher 视网膜病变是一种与创伤相关的威胁视力的闭塞性微血管病,在长骨骨折后很少见。

病例介绍

一名 20 岁女性在滑雪事故中与雪炮相撞,导致股骨干骨折(AO 32-A2.3),在事故后一小时接受了髓内钉治疗。手术后 14 小时,患者主诉双眼视力丧失,因此被转诊给神经科医生,此外还对大脑进行了 MRI 扫描。两者均未显示任何病理发现。患者最终被转至眼科。在裂隙灯检查和眼底检查后,诊断为 Purtscher 视网膜病变。诊断后立即开始治疗,症状出现后 5 天开始。患者接受了 5 天的静脉血液流变学治疗以及治疗剂量的低分子肝素和 Vasonit®400mg bid 口服。在 4 周和 6 个月的随访中,视力在 4 周前的那次检查中有所改善。在最终随访时,症状几乎完全缓解,未矫正视力(UCVA)和最佳矫正视力从最初双眼的 0.25 十进制提高到双眼的 0.8 十进制 UCVA 和 BCVA。

结论

术后视力丧失的患者必须尽快转至眼科和神经科进行评估。创伤和视力丧失的病史可能提示 Purtscher 视网膜病变的诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12ac/3936909/754f572f7f6d/1471-2474-15-42-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12ac/3936909/1fb9ac8d3ad8/1471-2474-15-42-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12ac/3936909/754f572f7f6d/1471-2474-15-42-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12ac/3936909/1fb9ac8d3ad8/1471-2474-15-42-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12ac/3936909/754f572f7f6d/1471-2474-15-42-2.jpg

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