诱导型一氧化氮合酶对于浆细胞的存活至关重要。
Inducible nitric oxide synthase is crucial for plasma cell survival.
机构信息
Emory Vaccine Center, Department of Microbiology & Immunology and Yerkes National Primate Center, Emory University, Atlanta, Georgia, USA.
出版信息
Nat Immunol. 2014 Mar;15(3):219-21. doi: 10.1038/ni.2831.
Abstract
The viability of long-lived plasma cells is enhanced by the expression of inducible nitric oxide synthase, which relieves endoplasmic reticulum stress by triggering a response dependent on cGMP and protein kinase G.
摘要
诱导型一氧化氮合酶的表达增强了长寿浆细胞的活力，通过触发依赖于 cGMP 和蛋白激酶 G 的反应来缓解内质网应激。
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