Mir Adnan, Chamlin Sarah L
Pediatr Ann. 2014 Jan 1;43(1):e13-5. doi: 10.3928/00904481-20131223-11.
A healthy 1-year-old boy born at full term after an uncomplicated pregnancy presented to the dermatology clinic for a widespread eruption with gradual onset since 3 months of age. He was otherwise well, afebrile, feeding well, and gaining weight appropriately. The child was overall asymptomatic, though some of his lesions occasionally became red and pruritic. His mother noticed that after mild illnesses, he was more prone to these flares. She denied flushing, vomiting, diarrhea, respiratory distress, and irritability. He was meeting all developmental milestones and started walking at 11 months of age. The remainder of his review of systems was unremarkable, and family history was noncontributory. Physical exam revealed a well-appearing, well-nourished, playful, and interactive toddler. There were innumerable discrete and coalescing pink-brown macules and papules concentrated on the trunk and extending onto the proximal upper and lower extremities bilaterally, as well as the neck and lower face. Stroking the lesions quickly led to development of erythematous edematous wheals. There was no hepatosplenomegaly, and the lymph node exam was unremarkable.
一名健康的1岁男童，足月顺产，孕期无并发症，因自3个月大起逐渐出现广泛皮疹前来皮肤科诊所就诊。他其他方面情况良好，无发热，喂养良好，体重增长正常。患儿总体无症状，不过其部分皮损偶尔会变红并伴有瘙痒。他的母亲注意到，在患轻度疾病后，他更容易出现这些皮疹发作。她否认有脸红、呕吐、腹泻、呼吸窘迫及易激惹症状。他达到了所有发育里程碑，11个月大时开始走路。系统回顾的其余部分无异常，家族史也无参考价值。体格检查显示，这是一个看起来健康、营养良好、活泼且互动性强的幼儿。有无数散在及融合的粉褐色斑疹和丘疹，集中于躯干，双侧延伸至近端上肢和下肢，以及颈部和下脸部。轻划皮损很快会导致红斑性水肿风团出现。无肝脾肿大，淋巴结检查无异常。
