Whittington Adam, Kenner-Bell Brandi
Pediatr Ann. 2014 Jan 1;43(1):e25-7. doi: 10.3928/00904481-20131223-15.
A 7-week-old boy presented to the pediatric dermatology clinic for evaluation of diffuse blue lesions on the skin. The mother first noticed a bluish lesion on the left thigh at 6 to 7 weeks of age. The child quickly developed several similar lesions and deeper nodules on the head, arms, and trunk. He had a history of ankyloglossia and subsequent uncomplicated repair, as well as a sister with neonatal anemia. He was otherwise well and thriving. Review of systems was unremarkable. His birth involved an uncomplicated delivery, with negative maternal serology. There was no history of maternal infection or recent exposure to infection. Physical exam revealed a well-appearing, non-dysmorphic, vigorous infant. Skin exam was notable for numerous dusky erythematous and violaceous-blue patches and nodules on the anterior scalp, bilateral arms, legs, face, and trunk - including the diaper area. Lesions ranged in size from 1 to 3 cm. The nodules were firm and non-tender. The remainder of his physical examination was normal without abnormal lymphadenopathy or hepatosplenomegaly noted. No mucosal lesions were noted. A biopsy was performed on a thigh lesion.
一名7周大的男婴前往儿科皮肤科诊所，接受皮肤弥漫性蓝色病变评估。母亲在孩子6至7周大时首次注意到左大腿上有一个蓝色病变。孩子很快在头部、手臂和躯干上出现了几个类似的病变以及更深的结节。他有舌系带过短并随后进行了无并发症修复的病史，还有一个患有新生儿贫血的姐姐。除此之外，他身体健康，发育良好。系统回顾无异常。他的出生过程顺利，母亲血清学检查阴性。无母亲感染史或近期感染接触史。体格检查显示是一名外表健康、无畸形、活力充沛的婴儿。皮肤检查发现，在前额头皮、双侧手臂、腿部、面部和躯干（包括尿布区域）有许多暗红斑和紫蓝色斑片及结节。病变大小从1厘米到3厘米不等。结节质地坚硬，无压痛。他其余的体格检查正常，未发现异常淋巴结肿大或肝脾肿大。未发现黏膜病变。对大腿部病变进行了活检。
