Crabtree Nutrition Laboratories, McGill University Health Centre/Royal Victoria Hospital, Montreal, QC, Canada H3H 1A1 ; Crabtree Nutrition Laboratories, McGill University Health Centre/Royal Victoria Hospital H6.90, 687 Pine Avenue West, Montreal, QC, Canada H3A 1A1.
Department of Pathology and Molecular Medicine, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada L8N 3Z5 ; Toronto 3D Knowledge Synthesis and Clinical Trials Unit, Clinical Nutrition and Risk Factor Modification Centre, St. Michael's Hospital, Toronto, ON, Canada M5C 2T2.
Int J Endocrinol. 2014;2014:151068. doi: 10.1155/2014/151068. Epub 2014 Jan 16.
The Transcultural Diabetes Nutrition Algorithm (tDNA) is a clinical tool designed to facilitate implementation of therapeutic lifestyle recommendations for people with or at risk for type 2 diabetes. Cultural adaptation of evidence-based clinical practice guidelines (CPG) recommendations is essential to address varied patient populations within and among diverse regions worldwide. The Canadian version of tDNA supports and targets behavioural changes to improve nutritional quality and to promote regular daily physical activity consistent with Canadian Diabetes Association CPG, as well as channelling the concomitant management of obesity, hypertension, dyslipidemia, and dysglycaemia in primary care. Assessing glycaemic index (GI) (the ranking of foods by effects on postprandial blood glucose levels) and glycaemic load (GL) (the product of mean GI and the total carbohydrate content of a meal) will be a central part of the Canadian tDNA and complement nutrition therapy by facilitating glycaemic control using specific food selections. This component can also enhance other metabolic interventions, such as reducing the need for antihyperglycaemic medication and improving the effectiveness of weight loss programs. This tDNA strategy will be adapted to the cultural specificities of the Canadian population and incorporated into the tDNA validation methodology.
跨文化糖尿病营养算法（tDNA）是一种临床工具，旨在促进实施 2 型糖尿病患者或有患病风险者的治疗性生活方式建议。对基于证据的临床实践指南（CPG）建议进行文化适应性调整对于解决全球不同地区和不同人群中的各种患者群体至关重要。加拿大版 tDNA 支持和针对行为改变，以提高营养质量，并促进与加拿大糖尿病协会 CPG 一致的日常定期身体活动，同时管理肥胖、高血压、血脂异常和糖尿病前期。评估血糖指数（GI）（根据对餐后血糖水平的影响对食物进行排名）和血糖负荷（GL）（平均 GI 与膳食总碳水化合物含量的乘积）将成为加拿大 tDNA 的核心部分，并通过使用特定食物选择促进血糖控制来补充营养治疗。这一组成部分还可以增强其他代谢干预措施，例如减少对降血糖药物的需求和提高减肥计划的有效性。这种 tDNA 策略将适应加拿大人口的文化特殊性，并纳入 tDNA 验证方法学。
