恶性风险指数用于术前盆腔肿物的评估。
Risk of malignancy index as an evaluation of preoperative pelvic mass.
作者信息
Bouzari Zinatossadat, Yazdani Shahla, Shirkhani Kelagar Ziba, Abbaszadeh Narges
机构信息
Department of Obstetrics & Gynecology, Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran.
Babol University of Medical Sciences, Babol, Iran.
出版信息
Caspian J Intern Med. 2011 Fall;2(4):331-5.
BACKGROUND
Risk of malignancy index (RMI) is the best method for discriminating benign and malignant pelvic masses. The aim of this study was to determine the RMI for preoperative evaluation of pelvic mass.
METHODS
This study was performed on 182 women with adenexal mass referred to Yahyahnejiad Hospital of Babol University of Medical Sciences in Iran from 2007 to 2009.The sensitivity, specificity, positive (PPV) and negative predictive values (NPV) of menopausal status, ultrasound finding of pelvic mass and level of serum CA-125, separately or combined into the RMI were calculated and compared.
RESULTS
The mean age of patients was 39.9±9.3 years. The RMI with the cut-off point of 265 had a sensitivity of 91.3%, specificity of 96.2 %, PPV of 77.7% and NPV of 98.7% for diagnosis of malignant masses.
CONCLUSION
Risk of malignancy index should be an effective method for evaluating a patient with adnexal masses before operation and a cut-off point of 265 which has a very high sensitivity, specificity and positive and negative predictive values for discriminating malignant and benign pelvic masses.
背景
恶性风险指数（RMI）是鉴别盆腔肿块良恶性的最佳方法。本研究的目的是确定用于盆腔肿块术前评估的RMI。
方法
本研究对2007年至2009年转诊至伊朗巴博勒医科大学亚亚赫内贾德医院的182例附件肿块女性患者进行。分别计算并比较绝经状态、盆腔肿块超声检查结果和血清CA-125水平单独或合并到RMI中的敏感性、特异性、阳性预测值（PPV）和阴性预测值（NPV）。
结果
患者的平均年龄为39.9±9.3岁。截断值为265时，RMI诊断恶性肿块的敏感性为91.3%，特异性为96.2%，PPV为77.7%，NPV为98.7%。
结论
恶性风险指数应是术前评估附件肿块患者的有效方法，截断值265对鉴别盆腔肿块的良恶性具有很高的敏感性、特异性以及阳性和阴性预测值。
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