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马乔林溃疡中的色素性基底细胞癌

Pigmented Basal Cell Carcinoma in Marjolin's Ulcer.

作者信息

Ghalige Hemanth Sureshwara, Karthik K, Rathod Sanjeev Somashekar, Bojen Ngangbam, Devi S Ranita

机构信息

Junior Resident, Department of General Surgery, Regional Institute of Medical Sciences , Imphal, Manipur, India .

Associate Professor, Department of General Surgery, Regional Institute of Medical Sciences , Imphal, Manipur, India .

出版信息

J Clin Diagn Res. 2013 Dec;7(12):2990-1. doi: 10.7860/JCDR/2013/6456.3721. Epub 2013 Dec 15.

DOI:10.7860/JCDR/2013/6456.3721
PMID:24551702
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3919297/
Abstract

Marjolin's ulcer is a carcinoma that develops in chronic benign ulcers or scars. It was first found to be associated with chronic osteomyelitis. Squamous cell carcinoma is the most common cancer which is being noted in Marjolin's ulcer. Suspicion of such lesions should be raised in chronic wounds which demonstrate characteristic changes. Diagnosis is made by doing a biopsy and it is treated by wide local excision. We are reporting here a case of 65-year-old female who presented with a growth in a long standing scar over her back. Scar was caused by an incision and drainage for an abscess performed 30 years back. On biopsy, features of pigmented variety of Basal Cell Carcinoma (BCC) were seen. Though occurrence of basal cell carcinoma in Marjolin's ulcer is known, pigmented variety is yet to be reported. The rare varieties like pigmented type of basal cell carcinoma in Marjolin's ulcer, must be borne in mind by histopathologists.

摘要

马乔林溃疡是一种发生于慢性良性溃疡或瘢痕的癌。它最初被发现与慢性骨髓炎有关。鳞状细胞癌是马乔林溃疡中最常见的癌症。对于出现特征性变化的慢性伤口,应提高对此类病变的怀疑。通过活检进行诊断,并采用广泛局部切除进行治疗。我们在此报告一例65岁女性病例,该患者背部长期存在的瘢痕处出现肿物。瘢痕是30年前因脓肿切开引流所致。活检显示为色素沉着型基底细胞癌(BCC)的特征。虽然已知基底细胞癌可发生于马乔林溃疡,但色素沉着型尚未见报道。组织病理学家必须牢记马乔林溃疡中色素沉着型基底细胞癌等罕见类型。

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本文引用的文献

1
Advanced Marjolin's ulcer of the scalp in a 13-year-old boy treated by excision and free tissue transfer: Case report and review of literature.13岁男孩头皮晚期马乔林溃疡的切除及游离组织移植治疗:病例报告并文献复习
Indian J Plast Surg. 2009 Jan-Jun;42(1):106-11. doi: 10.4103/0970-0358.53020.
2
Is surgery an effective and adequate treatment in advanced Marjolin's ulcer?手术对于晚期马乔林溃疡是一种有效且充分的治疗方法吗?
Burns. 2005 Jun;31(4):421-31. doi: 10.1016/j.burns.2005.02.008. Epub 2005 Apr 1.
3
SQUAMOUS-CELL CARCINOMA DEVELOPING IN THE CHRONIC DRAINING SINUSES OF OSTEOMYELITIS.
Cancer. 1965 Jan;18:128-32. doi: 10.1002/1097-0142(196501)18:1<128::aid-cncr2820180118>3.0.co;2-y.