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慢性伤口中的马乔林溃疡——现有文献综述

Marjolin's ulcer in chronic wounds - review of available literature.

作者信息

Bazaliński Dariusz, Przybek-Mita Joanna, Barańska Beata, Więch Paweł

机构信息

1Institute of Nursing and Health Sciences, Medical Faculty, University of Rzeszow, Rzeszów, Poland.

Podkarpackie Oncology Centre Specialist Hospital, Brzozów, Poland.

出版信息

Contemp Oncol (Pozn). 2017;21(3):197-202. doi: 10.5114/wo.2017.70109. Epub 2017 Sep 29.

DOI:10.5114/wo.2017.70109
PMID:29180925
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5701580/
Abstract

Marjolin's ulcer is a rare, aggressive skin cancer developing in scar tissue, chronic ulcers and areas affected by inflammations. Its incidence is estimated to range from 1% to 2% of all burn scars. It most frequently takes the form of squamous cell carcinoma which sometimes is diagnosed during examination of lesions developing in scars and hard-to-heal chronic wounds (pressure sores, leg ulcers). Therapeutic management of Marjolin's ulcer requires well-designed treatment plan to ensure optimal medical care and good quality of life for the patient. The high risk of metastases and damage to the structure of vitally important organs determines the need for early diagnosis and prompt surgical intervention with supplementary therapy. The purpose of the study was to examine etiopathogenesis of Marjolin's ulcer and principles of its treatment. The authors focused on the aspect of malignant degeneration in chronic wounds (leg ulcers, pressure sores) as a very rare, aggressive form of Marjolin's ulcer. A review of the available literature on the issue of Marjolin ulcers was conducted using the key words; Marjolin ulcers, pressure sore, chronic wound. Malignant degeneration in chronic wounds is a very rare aggressive form of Marjolin ulcer. Increased oncological alertness should be displayed by nursing and medical personnel taking care of patients with chronic wounds.

摘要

马乔林溃疡是一种罕见的侵袭性皮肤癌,发生于瘢痕组织、慢性溃疡及炎症累及部位。据估计,其发病率占所有烧伤瘢痕的1%至2%。它最常表现为鳞状细胞癌,有时在检查瘢痕及难愈合的慢性伤口(压疮、腿部溃疡)中出现的病变时被诊断出来。马乔林溃疡的治疗管理需要精心设计的治疗方案,以确保为患者提供最佳医疗护理和良好生活质量。转移风险高以及对重要器官结构的损害决定了需要早期诊断并及时进行手术干预及辅助治疗。本研究的目的是探讨马乔林溃疡的病因发病机制及其治疗原则。作者关注慢性伤口(腿部溃疡、压疮)中恶性变这一非常罕见的侵袭性马乔林溃疡形式。使用关键词“马乔林溃疡、压疮、慢性伤口”对关于马乔林溃疡问题的现有文献进行了综述。慢性伤口中的恶性变是一种非常罕见的侵袭性马乔林溃疡形式。护理和医疗人员在照顾慢性伤口患者时应提高肿瘤学警惕性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b29/5701580/5854ba72810b/WO-21-30590-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b29/5701580/fb2f423cc7c0/WO-21-30590-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b29/5701580/5854ba72810b/WO-21-30590-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b29/5701580/fb2f423cc7c0/WO-21-30590-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b29/5701580/5854ba72810b/WO-21-30590-g002.jpg

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