Imai Takanori, Sugizaki Chizuko, Ebisawa Motohiro
Department of Pediatrics, Showa University School of Medicine.
Clinical Research Center for Allergy and Rheumatology, National Hospital Organization, National Sagamihara Hospital.
Arerugi. 2013 Nov;62(11):1515-21.
Adrenaline administration is a top priority treatment for severe anaphylaxis. A survey with regard to the timing of adrenaline administration for anaphylaxis was conducted among physicians in Japan.
The survey was conducted using a questionnaire among physicians who had contributed to a nationwide survey for acute food allergy monitoring in 2011. The questionnaire comprised questions asking physicians whether they possessed registrations as an adrenaline self-injector (ASJ), and timing of adrenaline administration for anaphylaxis. Symptoms of anaphylaxis were categorized into shock or respiratory, gastrointestinal, cutaneous, or laryngeal symptoms.
A total of 674 replies were obtained from physicians, and 547 physicians were reported to be registered as ASJs. With regard to time, when patients injected themselves with adrenaline, it resulted in laryngeal (78.4%) and circulatory symptoms (64.4%), whereas when physicians administered adrenaline in patients, it resulted in circulatory (74.8%) and laryngeal symptoms (70.0%).
Japanese physicians did not necessarily understand the timing of adrenaline administration. Therefore, it is important to provide appropriate education to these physicians with regard to anaphylaxis and ASJ.
肾上腺素给药是严重过敏反应的首要治疗方法。在日本医生中进行了一项关于过敏反应肾上腺素给药时机的调查。
该调查通过问卷对参与2011年全国急性食物过敏监测调查的医生进行。问卷包括询问医生是否拥有肾上腺素自动注射器(ASJ)注册以及过敏反应肾上腺素给药时机的问题。过敏反应症状分为休克或呼吸、胃肠道、皮肤或喉部症状。
共收到医生674份回复,其中547名医生报告注册为ASJ。关于时间,当患者自行注射肾上腺素时,导致喉部症状(78.4%)和循环系统症状(64.4%),而当医生给患者注射肾上腺素时,导致循环系统症状(74.8%)和喉部症状(70.0%)。
日本医生不一定了解肾上腺素给药时机。因此,对这些医生进行关于过敏反应和ASJ的适当教育很重要。