Niu Jingjing, Seo Dong-Chul
Indiana University School of Public Health, Bloomington, IN, USA.
Ewha Womans University, Seoul, South Korea.
Prev Med. 2014 May;62:113-8. doi: 10.1016/j.ypmed.2014.02.012. Epub 2014 Feb 16.
In Chinese adults, the trend of central obesity and its longitudinal association with hypertension, independent of general obesity, was examined.
A 12-year longitudinal analysis was conducted using data retrieved from the China Health and Nutrition Survey. This study examined 6096 individuals (normotensive in 1997) who were followed up with in 2000, 2004, 2006, and 2009. Prevalence of hypertension in 2009 was predicted by baseline central obesity and waist circumference changes during a 12-year follow-up period along with confounding covariates using multiple logistic regressions.
Between 1997 and 2009, the prevalence of central obesity increased from 17.3% to 39.4% and was highest among individuals ≥60 years of age in 1997. By 2009, 26.8% of the participants developed hypertension. The odds ratio of developing hypertension during the 12-year study period for Chinese adults with central obesity at baseline was 1.79 (95% confidence interval=1.36-2.35) compared to those without central obesity, controlling for general obesity, demographics, smoking/drinking behavior, and fat intake.
Among Chinese adults, central obesity increases the risk for developing hypertension later in life, even after controlling for general obesity, smoking, drinking, and high fat intake among other factors. Waist circumference should be targeted in the efforts of hypertension prevention.
研究中国成年人中心性肥胖的趋势及其与高血压的纵向关联（独立于一般肥胖）。
利用中国健康与营养调查的数据进行了为期12年的纵向分析。本研究对6096名个体（1997年血压正常）进行了随访，随访时间分别为2000年、2004年、2006年和2009年。采用多元逻辑回归分析，通过基线中心性肥胖和12年随访期间腰围变化以及混杂协变量来预测2009年高血压的患病率。
1997年至2009年期间，中心性肥胖的患病率从17.3%增至39.4%，且在1997年年龄≥60岁的个体中最高。到2009年，26.8%的参与者患上了高血压。在控制了一般肥胖、人口统计学特征、吸烟/饮酒行为和脂肪摄入量后，基线时患有中心性肥胖的中国成年人在12年研究期间患高血压的优势比为1.79（95%置信区间=1.36 - 2.35），而无中心性肥胖者则较低。
在中国成年人中，即使在控制了一般肥胖、吸烟、饮酒和高脂肪摄入等其他因素后，中心性肥胖仍会增加日后患高血压的风险。在预防高血压的工作中应将腰围作为目标。
