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Dire Dawa地区成年人中高血压、高血糖和腹型肥胖的聚集性:一项基于社区的横断面研究。

Clustering of Elevated Blood Pressure, Elevated Blood Glucose, and Abdominal Obesity Among Adults in Dire Dawa: A Community-Based Cross-Sectional Study.

作者信息

Mengesha Melkamu Merid, Ayele Behailu Hawulte, Beyene Addisu Shunu, Roba Hirbo Shore

机构信息

Haramaya University, College of Health and Medical Sciences, School of Public Health, Department of Epidemiology and Biostatistics, Harar, Ethiopia.

Haramaya University, College of Health and Medical Sciences, School of Public Health, Department of Public Health and Health Policy, Harar, Ethiopia.

出版信息

Diabetes Metab Syndr Obes. 2020 Jun 16;13:2013-2024. doi: 10.2147/DMSO.S250594. eCollection 2020.

Abstract

BACKGROUND

Evidence shows that the presence of a single component of the metabolic syndrome (MetS) increases the risk of developing the MetS later in life. This study estimated the prevalence and associated factors of abdominal obesity, elevated blood pressure, elevated blood glucose, and the 3-factor MetS components among urban adults in Dire Dawa, East Ethiopia.

METHODS

Community-based cross-sectional data were collected from 872 adults aged 25-64 years. The joint interim statement (JIS) was used to define the MetS components. The dependent outcome variables were both the individual and the 3-factor MetS components. A robust variance Poisson regression model was used to directly estimate the prevalence ratio (PR) of risk factors.

RESULTS

The prevalence of the 3-factor MetS components (abdominal obesity, elevated blood pressure, and elevated blood glucose) was 9.5% (95% CI: 7.7, 11.7). Women had two times higher prevalence of the 3-factor MetS components compared with men, 11.6% (95% CI: 9.2, 14.5) vs 5.2% (95% CI: 3.2, 8.5). A higher prevalence of abdominal obesity, 46.4% (95% CI: 43.1, 49.8), followed by a raised blood pressure, 42.7% (95% CI: 39.4, 46.0), was observed among study subjects. The presence of a single MetS component had an associated cluster of other components: 33.7% of subjects with elevated blood glucose, 22.3% with elevated blood pressure, and 20.5% with abdominal obesity had also the 3-factor MetS components. Age, sex, body mass index, waist circumference, and physical activity were significantly associated with the individual components or the 3-factor MetS components.

CONCLUSION

A higher prevalence of the individual components and the presence of clustering with a single factor identified call for the need of community screening. Interventions targeting both abdominal and general obesity through physical activity and lifestyle modification can contribute towards reducing cardiometabolic risk factors with due attention given to women and older adults.

摘要

背景

有证据表明,代谢综合征(MetS)单一成分的存在会增加日后患MetS的风险。本研究估算了埃塞俄比亚东部德雷达瓦市城市成年人中腹型肥胖、血压升高、血糖升高以及三因素MetS成分的患病率及相关因素。

方法

收集了872名年龄在25 - 64岁成年人的基于社区的横断面数据。采用联合临时声明(JIS)来定义MetS成分。相关结局变量为个体及三因素MetS成分。使用稳健方差泊松回归模型直接估算危险因素的患病率比(PR)。

结果

三因素MetS成分(腹型肥胖、血压升高和血糖升高)的患病率为9.5%(95%置信区间:7.7,11.7)。女性三因素MetS成分的患病率是男性的两倍,分别为11.6%(95%置信区间:9.2,14.5)和5.2%(95%置信区间:3.2,8.5)。研究对象中腹型肥胖的患病率较高,为46.4%(95%置信区间:43.1,49.8),其次是血压升高,为42.7%(95%置信区间:39.4,46.0)。单一MetS成分的存在与其他成分存在关联集群:血糖升高的受试者中有33.7%、血压升高的受试者中有22.3%以及腹型肥胖的受试者中有20.5%同时患有三因素MetS成分。年龄、性别、体重指数、腰围和身体活动与个体成分或三因素MetS成分显著相关。

结论

个体成分的高患病率以及单一因素聚类的存在表明需要进行社区筛查。通过身体活动和生活方式改变针对腹型肥胖和全身肥胖的干预措施,在充分关注女性和老年人的情况下,有助于降低心血管代谢危险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8176/7305819/a85293353b70/DMSO-13-2013-g0001.jpg

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