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用防菌斑剂改性的正畸光活化粘合剂的抗菌性能和物理性能评估:一项体外研究。

Evaluation of the antimicrobial and physical properties of an orthodontic photo-activated adhesive modified with an antiplaque agent: an in vitro study.

作者信息

Singh Chanjyot, Dua Vinay, Vyas Matrishva, Verma Sanjeev

机构信息

Department of Orthodontics, MMCDSR, MM University, Mullana, Haryana, India.

出版信息

Indian J Dent Res. 2013 Nov-Dec;24(6):694-700. doi: 10.4103/0970-9290.127613.

Abstract

INTRODUCTION

This study was designed to investigate the antimicrobial and physical properties of orthodontic composite resin modified by the addition of an antimicrobial agent.

MATERIALS AND METHODS

Transbond XT (3M Unitek), a photo-activated, light-cured composite resin, modified by the addition of chlorhexidine, in concentrations 2.5 wt% was formed into a uniform disc and also used for direct bonding of the brackets on the freshly extracted premolars for testing. The tablets of each group and a control group were subjected to the agar plate diffusion test to measure the zone of bacterial inhibition. In addition, they were incubated for 24 h in brain heart infusion medium inoculated with Streptococcus mutans and examined for antimicrobial action. A total of 80 extracted premolars were collected and divided into two sets of 40 teeth each. Stainless steel preadjusted edgewise appliance (PEA) brackets were bonded by using control and experimental composites. A universal testing machine was used to determine the shear bond strength. The first set of teeth was tested after 24 h and the second set after 25 days of storage in distilled water. Time-dependent release of antimicrobial agents from the modified composites was also monitored spectrophotometrically.

RESULTS

The findings indicated that (1) addition of chlorhexidine to the orthodontic composite resin enhanced its antimicrobial properties, (2) there was no significant difference between the bond strengths of the control and the experimental resins tested after 24 h and 25 days and (3) maximum release of chlorhexidine from the modified resin was much higher than the minimum inhibitory concentration level.

摘要

引言

本研究旨在探究添加抗菌剂后正畸复合树脂的抗菌性能和物理性能。

材料与方法

将Transbond XT(3M Unitek),一种光活化、光固化复合树脂,添加浓度为2.5 wt%的洗必泰进行改性,制成均匀的圆盘,还用于将托槽直接粘结在新鲜拔除的前磨牙上进行测试。对每组片剂和一个对照组进行琼脂平板扩散试验,以测量抑菌圈。此外,将它们在接种变形链球菌的脑心浸液培养基中孵育24小时,并检测其抗菌作用。共收集80颗拔除的前磨牙,分为两组,每组40颗牙齿。使用对照复合材料和实验复合材料粘结不锈钢预调整直丝弓矫治器(PEA)托槽。使用万能试验机测定剪切粘结强度。第一组牙齿在24小时后进行测试,第二组在蒸馏水中储存25天后进行测试。还通过分光光度法监测抗菌剂从改性复合材料中的时间依赖性释放。

结果

研究结果表明:(1)在正畸复合树脂中添加洗必泰可增强其抗菌性能;(2)在24小时和25天后测试的对照树脂和实验树脂的粘结强度之间没有显著差异;(3)改性树脂中洗必泰的最大释放量远高于最低抑菌浓度水平。

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