Costa Ana Lúcia do Rêgo Rodrigues, Araujo Júnior Edward, Lima José Wellington de Oliveira, Costa Fabrício da Silva
Universidade Estadual do Ceará, FortalezaCE, Brasil, Universidade Estadual do Ceará - UECE - Fortaleza (CE), Brasil.
Universidade Federal de São Paulo, Escola Paulista de Medicina, Departamento de Obstetrícia, São PauloSP, Brasil, Departamento de Obstetrícia da Escola Paulista de Medicina; Universidade Federal de São Paulo - UNIFESP - São Paulo (SP), Brasil.
Rev Bras Ginecol Obstet. 2014 Jan;36(1):29-34. doi: 10.1590/S0100-72032014000100007.
To evaluate the maternal risk factors that require newborn assistance in neonatal Intensive Care Units (ICU).
A prospective observational case-control study was conducted on 222 pregnant women (1:1 case-control ratio) attended at a public maternity. The following variables were analyzed in the puerperae: age at menarche, age at first sexual intercourse, history of chronic diseases, habits, prenatal care, obstetric history, clinical complications during pregnancy and childbirth, and sociodemographic variables. The variables of the newborns were: Apgar scores, gestational age, birth weight, presence or absence of malformation, need for resuscitation, and complications during the first 24 hours. Proportions were compared using the Fisher exact test or the Person γ2 test. Multivariable models were developed by logistic regression analysis using adjusted Odds Ratio with a 95% confidence interval (CI).
Regarding reproductive history, ≥3 pregnancies and 2 or 3 previous cesareans were sytatistically significant (p=0.0 and 0.0, respectively). Among the complications that required assistance in the neonatal ICU, prematurity was responsible for 61 cases (55.5%), followed by risk of intrapartum infection in 46 cases (41.8%). Regarding the maternal history, the presence of hypertensive disease showed statistical significance (p=0.0). Premature rupture of membranes was strongly associated with the need for the neonatal ICU (Odds Ratio - OR=6.1, 95%CI 2.6-14.4).
Premature rupture of membranes and hypertensive disease should receive special attention in prenatal care due to their strong association with newborns requiring assistance in the neonatal ICU.
评估新生儿重症监护病房(ICU)中需要新生儿辅助的孕产妇风险因素。
对一家公立产科收治的222名孕妇(病例对照比例为1:1)进行了一项前瞻性观察性病例对照研究。分析了产妇的以下变量:初潮年龄、首次性交年龄、慢性病病史、习惯、产前护理、产科病史、妊娠和分娩期间的临床并发症以及社会人口统计学变量。新生儿的变量包括:阿氏评分、胎龄、出生体重、是否存在畸形、复苏需求以及出生后24小时内的并发症。使用Fisher精确检验或Person γ2检验比较比例。通过逻辑回归分析建立多变量模型,使用调整后的优势比及95%置信区间(CI)。
关于生殖史,≥3次妊娠以及既往有2次或3次剖宫产在统计学上具有显著意义(分别为p = 0.0和0.0)。在需要新生儿ICU辅助的并发症中,早产导致61例(55.5%),其次是产时感染风险46例(41.8%)。关于孕产妇病史,高血压疾病的存在具有统计学意义(p = 0.0)。胎膜早破与新生儿ICU需求密切相关(优势比 - OR = 6.1,95%CI 2.6 - 14.4)。
由于胎膜早破和高血压疾病与需要新生儿ICU辅助的新生儿密切相关,因此在产前护理中应给予特别关注。