Madan Ichchha, Puri Isha, Jain Neetu J, Grotegut Chad, Nelson Deb, Dandolu Vani
Department of Obstetrics and Gynecology, Temple University Hospital, Philadelphia, PA 19140, USA.
J Matern Fetal Neonatal Med. 2009 Sep;22(9):785-90. doi: 10.3109/14767050902874097.
To assess the demographic characteristics, risk factors and perinatal outcomes among maternal intensive care unit (ICU) admissions in New Jersey from 1997 to 2005.
Data were obtained from a perinatal linked database from MCH epidemiology programme in New Jersey. Chi-square test was used for bivariate analysis and stepwise logistic regression was used to assess the influence of the potential risk factors and pregnancy complications.
There were 15,447 (1.54%) ICU admissions and 23 maternal deaths (0.15%) among the 1,004,116 pregnancies. Analysis of demographic factors revealed that maternal age, race and smoking were significantly associated with ICU admission. Regression analysis adjusting for maternal age, parity, gravida, race, smoking status, maternal education and place of delivery found the following predictors for ICU admission, preeclampsia (odds ratio (OR): 2.8, 95% confidence interval (CI): 2.6-3.0), eclampsia (OR: 6.8, 95% CI: 5.4-8.6), placenta previa (OR: 3.0, 95% CI: 2.7-3.4), abruption (OR: 8.9, 95% CI: 8.3-9.6), multifetal pregnancy (OR: 4.2, 95% CI: 4.1-4.4), diabetes (OR: 3.1, 95% CI: 2.7-3.5), acute renal failure (OR: 22.1, 95% CI: 13.3-36.6) and cesarean delivery (OR: 1.9, 95% CI: 1.5-2.4). Infants born to ICU admitted mothers had higher rates of NICU admission, neonatal intubations and lower Apgar scores compared with infants born to non-ICU admitted mothers.
Pregnancy complications are predictive of ICU admission amongst pregnant patients after adjusting for demographic factors.
评估1997年至2005年新泽西州入住孕产妇重症监护病房（ICU）的患者的人口统计学特征、危险因素及围产期结局。
数据来源于新泽西州妇幼保健流行病学项目的围产期关联数据库。采用卡方检验进行双变量分析，并使用逐步逻辑回归来评估潜在危险因素和妊娠并发症的影响。
在1,004,116例妊娠中，有15,447例（1.54%）入住ICU，23例孕产妇死亡（0.15%）。人口统计学因素分析显示，孕产妇年龄、种族和吸烟与入住ICU显著相关。在对孕产妇年龄、产次、孕周、种族、吸烟状况、孕产妇教育程度和分娩地点进行校正的回归分析中，发现以下因素可预测入住ICU：先兆子痫（比值比（OR）：2.8，95%置信区间（CI）：2.6 - 3.0）、子痫（OR：6.8，95% CI：5.4 - 8.6）、前置胎盘（OR：3.0，95% CI：2.7 - 3.4）、胎盘早剥（OR：8.9，95% CI：8.3 - 9.6）、多胎妊娠（OR：4.2，95% CI：4.1 - 4.4）、糖尿病（OR：3.1，95% CI：2.7 - 3.5）、急性肾衰竭（OR：22.1，95% CI：13.3 - 36.6）和剖宫产（OR：1.9，95% CI：1.5 - 2.4）。与未入住ICU的母亲所生婴儿相比，入住ICU的母亲所生婴儿入住新生儿重症监护病房（NICU）的比例更高，接受新生儿插管的比例更高，阿氏评分更低。
在校正人口统计学因素后，妊娠并发症可预测孕妇入住ICU的情况。
