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澳大利亚、美国、斯堪的纳维亚影像交流组织（AUSSIE）：一个嵌入医疗保健体系的创新型虚拟整合健康研究网络。

The Australian, US, Scandinavian Imaging Exchange (AUSSIE): an innovative, virtually-integrated health research network embedded in health care.

作者信息

Looi Jeffrey Cl, Velakoulis Dennis, Walterfang Mark, Georgiou-Karistianis Nellie, Macfarlane Matthew D, Power Brian D, Nilsson Christer, Styner Martin, Thompson Paul M, Van Westen Danielle, Wilkes Fiona A, Wahlund Lars-Olof

机构信息

Academic Unit of Psychiatry and Addiction Medicine, Australian National University Medical School, Canberra, and; Mental Health Service, Australian Capital Territory Health Directorate, Canberra Hospital, Woden, ACT, Australia

Neuropsychiatry Unit, Royal Melbourne Hospital, Melbourne, and; Melbourne Neuropsychiatry Centre, University of Melbourne and Northwestern Mental Health, Melbourne, VIC, Australia.

出版信息

Australas Psychiatry. 2014 Jun;22(3):260-265. doi: 10.1177/1039856214523494. Epub 2014 Feb 19.

DOI:
10.1177/1039856214523494
PMID:24554532
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4276529/
Abstract

OBJECTIVE

To describe the development, design and function of an innovative international clinical research network for neuroimaging research, based in Australia, within a joint state health service/medical school. This Australian, US, Scandinavian Imaging Exchange (AUSSIE) network focuses upon identifying neuroimaging biomarkers for neuropsychiatric and neurodegenerative disease.

METHODS

We describe a case study of the iterative development of the network, identifying characteristic features and methods which may serve as potential models for virtual clinical research networks. This network was established to analyse clinically-derived neuroimaging data relevant to neuropsychiatric and neurodegenerative disease, specifically in relation to subcortical brain structures.

RESULTS

The AUSSIE network has harnessed synergies from the individual expertise of the component groups, primarily clinical neuroscience researchers, to analyse a variety of clinical data.

CONCLUSION

AUSSIE is an active virtual clinical research network, analogous to a connectome, which is embedded in health care and has produced significant research, advancing our understanding of neuropsychiatric and neurodegenerative disease through the lens of neuroimaging.

摘要

目的

描述一个创新的国际神经影像学研究临床研究网络的发展、设计和功能，该网络位于澳大利亚，隶属于州立卫生服务机构/医学院。这个澳大利亚、美国、斯堪的纳维亚影像交流（AUSSIE）网络专注于识别神经精神疾病和神经退行性疾病的神经影像学生物标志物。

方法

我们描述了该网络迭代发展的一个案例研究，确定了可能作为虚拟临床研究网络潜在模型的特征和方法。该网络旨在分析与神经精神疾病和神经退行性疾病相关的临床来源的神经影像数据，特别是与皮质下脑结构有关的数据。

结果

AUSSIE网络利用了各组成小组（主要是临床神经科学研究人员）的个人专业知识所产生的协同效应，来分析各种临床数据。

结论

AUSSIE是一个活跃的虚拟临床研究网络，类似于一个连接组，它融入了医疗保健体系，并开展了重要研究，通过神经影像学的视角增进了我们对神经精神疾病和神经退行性疾病的理解。