Pavlic Verica, Vujic-Aleksic Vesna, Zubovic Nina, Gojkov-Vukelic Mirjana
Department of Periodontology and Oral Medicine, Institute of Dentistry, Banja Luka, Bosnia and Herzegovina.
The Republic of Srpska Agency for Certification, Accreditation and Quality Improvement in Health Care, Banja Luka, Bosnia and Herzegovina.
Acta Inform Med. 2013 Dec;21(4):250-2. doi: 10.5455/aim.2013.21.250-252. Epub 2013 Dec 4.
Buerger's disease (BD) is a relatively rare thrombotic, occlusive and non-atherosclerotic clinical syndrome of unknown etiology. In recent years, numerous epidemiological studies confirmed the strong association between chronic anaerobic periodontal infection and development of cardiovascular diseases, including BD. Therefore, the aim of this study is to clarify association between periodontal pathogens and Buerger's disease. Confirmation of presence and identification of periopathogens in patients with BD can be considered crucial in developing novel therapies for BD. Further, periodontal therapy will lead to eventual improvement of BD patients' condition.
血栓闭塞性脉管炎(BD)是一种相对罕见的、病因不明的血栓形成、闭塞性和非动脉粥样硬化性临床综合征。近年来,大量流行病学研究证实慢性厌氧性牙周感染与包括BD在内的心血管疾病的发生之间存在密切关联。因此,本研究的目的是阐明牙周病原体与血栓闭塞性脉管炎之间的关联。确认BD患者中牙周病原体的存在并对其进行鉴定,对于开发BD的新疗法至关重要。此外,牙周治疗将最终改善BD患者的病情。