Levanti M C, Montisci R, Rosa M D, Sedda P, Del Fiacco M
Istituto di Anatomia Umana Normale, University of Cagliari, Italy.
Basic Appl Histochem. 1988;32(1):145-52.
The localization of substance P is studied in the human prevertebral sympathetic ganglia and descending colon by the indirect immunofluorescence technique. Strongly immunoreactive axons reach the coeliac, superior mesenteric and inferior mesenteric ganglia. The sympathetic postganglionic neurones are surrounded by a meshwork of positive beaded fibers and terminals. Varicose nerve fibers are variously distributed in all nonepithelial layers of the colon. A close network of fibers and terminal surrounds the ganglionic cells in the mienteric and submucous plexuses. Substance P-like immunoreactive perikarya are present in these structures.
采用间接免疫荧光技术研究了P物质在人椎前交感神经节和降结肠中的定位。强免疫反应性轴突到达腹腔神经节、肠系膜上神经节和肠系膜下神经节。交感神经节后神经元被阳性串珠状纤维和终末的网络所包围。曲张神经纤维以不同方式分布于结肠的所有非上皮层。纤维和终末的紧密网络围绕着肌间神经丛和黏膜下神经丛中的神经节细胞。这些结构中存在P物质样免疫反应性核周体。
