Karhula T, Soinila S, Lakomy M, Majewski M, Kaleczyk J, Häppölä O
Department of Anatomy, University of Helsinki, Finland.
Neurosci Lett. 1995 Jul 14;194(1-2):85-8. doi: 10.1016/0304-3940(95)11733-d.
Localization of 5-hydroxytryptamine immunoreactivity was studied in the rat coeliac-superior mesenteric ganglion complex and in the porcine superior and inferior mesenteric ganglia by the indirect immunofluorescence technique. In normal rats, only 5-hydroxytryptamine immunoreactive SIF cells were seen in the coeliac-superior mesenteric ganglion complex. In the rats, pretreated with a 5-hydroxytryptamine precursor, L-tryptophan, and with a monoamine oxidase inhibitor, nialamide, a large number of 5-hydroxytryptamine-immunoreactive nerve fiber terminals were detected. In normal porcine superior and inferior mesenteric ganglia, intense 5-hydroxytryptamine immunoreactivity was found in numerous nerve fibers which were located around tyrosine hydroxylase-immunoreactive principal neurons. The origin and function of these fibers are discussed.
采用间接免疫荧光技术研究了大鼠腹腔-肠系膜上神经节复合体以及猪肠系膜上、下神经节中5-羟色胺免疫反应性的定位。在正常大鼠中，仅在腹腔-肠系膜上神经节复合体中可见5-羟色胺免疫反应性的SIF细胞。在用5-羟色胺前体L-色氨酸和单胺氧化酶抑制剂尼亚酰胺预处理的大鼠中，检测到大量5-羟色胺免疫反应性神经纤维终末。在正常猪肠系膜上、下神经节中，在位于酪氨酸羟化酶免疫反应性主神经元周围的众多神经纤维中发现了强烈的5-羟色胺免疫反应性。讨论了这些纤维的起源和功能。
