Bhatia Gaurav, Lau Mary E, Koury Katharine M, Gulur Padma
Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Boston MA, 02114, USA.
F1000Res. 2013 Mar 28;2:96. doi: 10.12688/f1000research.2-96.v4. eCollection 2013.
Intrathecal drug delivery is an effective pain management option for patients with chronic and cancer pain. The delivery of drugs into the intrathecal space provides superior analgesia with smaller doses of analgesics to minimize side effects while significantly improving quality of life. This article aims to provide a general overview of the use of intrathecal drug delivery to manage pain, dosing recommendations, potential risks and complications, and growing trends in the field.
鞘内药物递送是慢性疼痛和癌痛患者有效的疼痛管理选择。将药物递送至鞘内空间可使用较小剂量的镇痛药提供卓越的镇痛效果,以尽量减少副作用,同时显著提高生活质量。本文旨在概述鞘内药物递送用于疼痛管理的情况、给药建议、潜在风险和并发症以及该领域的发展趋势。