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鞘内注射芬太尼泵植入治疗遗传性多发性骨软骨瘤所致慢性疼痛1例报告

Intrathecal Fentanyl Pump Placement in a Patient With Chronic Pain Caused by Hereditary Multiple Exostoses: A Case Report.

作者信息

Tageant Hayden, Jackson Corrie N, Varrassi Giustino, Pasqualucci Alberto, Shekoohi Sahar, Kaye Alan D

机构信息

School of Medicine, Louisiana State University Health Sciences Center, Shreveport, USA.

Pain Medicine, Fondazione Paolo Procacci, Rome, ITA.

出版信息

Cureus. 2024 Nov 7;16(11):e73240. doi: 10.7759/cureus.73240. eCollection 2024 Nov.

Abstract

Hereditary multiple exostoses (HME) is a genetic disorder defined by the formation of benign bone tumors known as exostoses, which can lead to chronic pain and functional impairment. This case report details a 57-year-old man with a long-standing history of severe diffuse bone pain attributed to HME. Despite various treatments, his pain remained poorly controlled until an intrathecal pump with fentanyl was implanted. This intervention significantly improved his pain management and overall quality of life. The manuscript explores clinical presentation, diagnostic approach, and treatment outcomes, highlighting the challenges and benefits of intrathecal drug delivery systems in managing refractory pain associated with HME.

摘要

遗传性多发性骨软骨瘤(HME)是一种遗传性疾病,其特征是形成称为骨软骨瘤的良性骨肿瘤,可导致慢性疼痛和功能障碍。本病例报告详细介绍了一名57岁男性,他长期患有因HME引起的严重弥漫性骨痛。尽管进行了各种治疗,他的疼痛仍控制不佳,直到植入了芬太尼鞘内泵。这一干预措施显著改善了他的疼痛管理和整体生活质量。本文探讨了临床表现、诊断方法和治疗结果,强调了鞘内给药系统在管理与HME相关的难治性疼痛方面的挑战和益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/013d/11625517/92d0e165483b/cureus-0016-00000073240-i01.jpg

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