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局麻药凝胶在男性门诊硬性膀胱镜检查中尿道内停留时间对疼痛感知的影响:一项随机前瞻性研究。

Effect of intraurethral dwell time of local anesthetic jelly on pain perception in men undergoing outpatient rigid cystoscopy: a randomized prospective study.

机构信息

Department of Urology, VMMC and Safdarjung Hospital , New Delhi, India .

出版信息

J Endourol. 2014 Jul;28(7):846-9. doi: 10.1089/end.2014.0015. Epub 2014 Mar 24.

Abstract

AIM

To determine optimum duration of intraurethral 2% lidocaine jelly for pain relief during outpatient rigid cystoscopy.

MATERIALS AND METHODS

This prospective randomized study was conducted between June 2012 and November 2013. Four hundred consecutive adult males requiring diagnostic rigid cystoscopy were randomized into four groups depending on intraurethral 2% lidocaine jelly dwell time before rigid cystoscopy: jelly was instilled 5, 10, 15, and 20 minutes before start of the procedure in group A, B, C, and D patients, respectively. The patients' age, patient-reported preoperative anxiety score, patient-reported intraoperative pain score, the surgeon-reported patient's pain score, and the duration of rigid cystoscopy were recorded and analyzed.

RESULTS

The mean age, patient-reported preoperative anxiety score, and duration of rigid cystoscopy were similar between the four groups with no significant difference noted between them. The least and highest mean patient-reported and surgeon-reported intraoperative pain scores were reported in group C (1.49±0.82 and 1.58±0.67) patients and group A (4.86±1.24 and 4.04±1.11) patients, respectively, while no significant difference was found in these scores between group C and D patients.

CONCLUSION

For male patients undergoing diagnostic rigid cystoscopy, an intraurethral dwell time of 15 minutes (of 20 mL 2% lidocaine jelly) provided optimum pain relief.

摘要

目的

确定门诊硬性膀胱镜检查中 2%利多卡因尿道内凝胶缓解疼痛的最佳作用时间。

材料和方法

本前瞻性随机研究于 2012 年 6 月至 2013 年 11 月进行。400 例需要诊断性硬性膀胱镜检查的成年男性患者,根据硬性膀胱镜检查前 2%利多卡因尿道内凝胶留置时间随机分为 4 组:A、B、C 和 D 组患者分别在开始检查前 5、10、15 和 20 分钟注入凝胶。记录并分析患者的年龄、患者术前焦虑评分、患者术中疼痛评分、手术医生报告的患者疼痛评分和硬性膀胱镜检查时间。

结果

四组患者的平均年龄、患者术前焦虑评分和硬性膀胱镜检查时间相似,组间无显著差异。C 组(1.49±0.82 和 1.58±0.67)和 A 组(4.86±1.24 和 4.04±1.11)患者报告的最低和最高平均患者报告和手术医生报告的术中疼痛评分分别为 1.49±0.82 和 1.58±0.67,C 组和 D 组患者之间这些评分无显著差异。

结论

对于行诊断性硬性膀胱镜检查的男性患者,15 分钟(20ml 2%利多卡因凝胶)的尿道内留置时间可提供最佳的疼痛缓解效果。

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