Gooran Shahram, Pourfakhr Pejman, Bahrami Shirin, Fakhr Yasseri Ali Mohammad, Javid Amir, Behtash Negar, Pourmand Gholamreza
Urology Research Center, Sina Hospital, Tehran University of Medical Sciences, Hassan-Abad Sq., Tehran, Iran.
Department of Anesthesiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Urol J. 2017 Jul 2;14(4):4044-4047.
Cystoscopy is one of the most common urologic procedures. The aim of this study is to investigate the combined effect of intraurethral lidocaine gel and intraglandular injection of lidocaine 2% on pain during and after cystoscopy. Materials & Methods: In this double-blind, parallel group randomized clinical trial, 156 patients referred for double J removal, urethral dilatation, or cystoscopy were enrolled. The patients were divided into two groups, A and B. All patients received 20 cc of intraurethral lidocaine gel 2%. In group A (N = 75), lidocaine 2% was also injected into the glans penis. The patients in group B (N = 81) only received the intraurethral lidocaine gel. Cystoscopy was performed 10 minutes later. The primary outcome of interest was measured in terms of pain score (visual analogue scale) during and 5 minutes after cystoscopy.
Immediate pain score after the procedure was 3.4 ± 3 and 4.6 ± 3 in groups A and B, respectively (P = .011).
Based on the findings of the present study, lidocaine injection into the glans penis significantly reducedpain perception.
膀胱镜检查是最常见的泌尿外科手术之一。本研究旨在探讨尿道内利多卡因凝胶与2%利多卡因腺体内注射联合应用对膀胱镜检查期间及术后疼痛的影响。材料与方法：在这项双盲、平行组随机临床试验中，纳入了156例因取出双J管、尿道扩张或膀胱镜检查而就诊的患者。患者分为A、B两组。所有患者均接受20毫升2%尿道内利多卡因凝胶。A组（N = 75）患者还在阴茎头注射了2%利多卡因。B组（N = 81）患者仅接受尿道内利多卡因凝胶。10分钟后进行膀胱镜检查。主要观察指标为膀胱镜检查期间及检查后5分钟的疼痛评分（视觉模拟量表）。
术后即刻疼痛评分，A组和B组分别为3.4±3和4.6±3（P = 0.011）。
基于本研究结果，阴茎头注射利多卡因可显著降低疼痛感知。
