一项比较联合腺体内利多卡因注射与尿道内利多卡因凝胶和单纯尿道内利多卡因凝胶用于膀胱镜检查和尿道扩张的随机对照试验。

A Randomized Control Trial Comparing Combined Glandular Lidocaine Injection and Intraurethral Lidocaine Gel with Intraurethral Lidocaine Gel Alone in Cystoscopy and Urethral Dilatation.

作者信息

Gooran Shahram, Pourfakhr Pejman, Bahrami Shirin, Fakhr Yasseri Ali Mohammad, Javid Amir, Behtash Negar, Pourmand Gholamreza

机构信息

Urology Research Center, Sina Hospital, Tehran University of Medical Sciences, Hassan-Abad Sq., Tehran, Iran.

Department of Anesthesiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Urol J. 2017 Jul 2;14(4):4044-4047.

PMID:28670677

Abstract

PURPOSE

Cystoscopy is one of the most common urologic procedures. The aim of this study is to investigate the combined effect of intraurethral lidocaine gel and intraglandular injection of lidocaine 2% on pain during and after cystoscopy. Materials & Methods: In this double-blind, parallel group randomized clinical trial, 156 patients referred for double J removal, urethral dilatation, or cystoscopy were enrolled. The patients were divided into two groups, A and B. All patients received 20 cc of intraurethral lidocaine gel 2%. In group A (N = 75), lidocaine 2% was also injected into the glans penis. The patients in group B (N = 81) only received the intraurethral lidocaine gel. Cystoscopy was performed 10 minutes later. The primary outcome of interest was measured in terms of pain score (visual analogue scale) during and 5 minutes after cystoscopy.

RESULTS

Immediate pain score after the procedure was 3.4 ± 3 and 4.6 ± 3 in groups A and B, respectively (P = .011).

CONCLUSION

Based on the findings of the present study, lidocaine injection into the glans penis significantly reducedpain perception.

摘要

目的

膀胱镜检查是最常见的泌尿外科手术之一。本研究旨在探讨尿道内利多卡因凝胶与2%利多卡因腺体内注射联合应用对膀胱镜检查期间及术后疼痛的影响。材料与方法：在这项双盲、平行组随机临床试验中，纳入了156例因取出双J管、尿道扩张或膀胱镜检查而就诊的患者。患者分为A、B两组。所有患者均接受20毫升2%尿道内利多卡因凝胶。A组（N = 75）患者还在阴茎头注射了2%利多卡因。B组（N = 81）患者仅接受尿道内利多卡因凝胶。10分钟后进行膀胱镜检查。主要观察指标为膀胱镜检查期间及检查后5分钟的疼痛评分（视觉模拟量表）。