木醋杆菌E25菌株的全基因组序列——细菌纳米纤维素的重要且高效生产者

Complete genome sequence of Gluconacetobacter xylinus E25 strain--valuable and effective producer of bacterial nanocellulose.

作者信息

Kubiak Katarzyna, Kurzawa Marta, Jędrzejczak-Krzepkowska Marzena, Ludwicka Karolina, Krawczyk Mariusz, Migdalski Andrzej, Kacprzak Magdalena M, Loska Damian, Krystynowicz Alina, Bielecki Stanisław

机构信息

Institute of Technical Biochemistry, Lodz University of Technology, Stefanowskiego 4/10, 90-924 Lodz, Poland.

出版信息

J Biotechnol. 2014 Apr 20;176:18-9. doi: 10.1016/j.jbiotec.2014.02.006. Epub 2014 Feb 17.

DOI:10.1016/j.jbiotec.2014.02.006

PMID:24556328

Abstract

This study reports the release of complete genome sequence of the producer of bacterial nanocellulose (BNC) - Gluconacetobacter xylinus E25, a vinegar-isolated strain. Preliminary sequence analysis revealed complexity of the genome structure and familiarized genetic basis of productive properties of E25 strain. The genome consists of one chromosome and five plasmids. Whole genome sequencing has opened up new perspectives for further bioinformatics and experimental studies allowing the elucidation of molecular mechanisms responsible for regulation of production of BNC - a valuable biomaterial.

摘要

本研究报告了细菌纳米纤维素（BNC）产生菌——木醋杆菌E25（一株从醋中分离出的菌株）完整基因组序列的发布。初步序列分析揭示了该基因组结构的复杂性，并使人们熟悉了E25菌株生产特性的遗传基础。该基因组由一条染色体和五个质粒组成。全基因组测序为进一步的生物信息学和实验研究开辟了新的前景，有助于阐明负责调控BNC（一种有价值的生物材料）生产的分子机制。