Lu Shuanglong, Wang Jiaqing, Cao Xueqin, Li Xinming, Gu Hongwei
Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou, 215123, China.
Chem Commun (Camb). 2014 Apr 4;50(26):3512-5. doi: 10.1039/c3cc48596j. Epub 2014 Feb 21.
A new one-pot method has been developed for the selective synthesis of secondary amines via reductive amination of the corresponding nitriles using Pt nanowires as a catalyst. This method allows for the synthesis of both unsymmetrical and symmetrical secondary amines in excellent yields (up to 95%) in the presence or absence of additional amines, respectively. Furthermore, the reaction proceeds under mild conditions and is environmentally benign.
已经开发出一种新的一锅法，用于通过使用铂纳米线作为催化剂对相应腈进行还原胺化来选择性合成仲胺。该方法分别在有或没有额外胺的情况下，以优异的产率（高达95%）合成不对称和对称仲胺。此外，该反应在温和条件下进行，且对环境友好。
