在斯里兰卡的一群医学生中，生活质量和潜在的生化指标与学业考试表现相关联的程度如何？
How does the quality of life and the underlying biochemical indicators correlate with the performance in academic examinations in a group of medical students of Sri Lanka?
机构信息
Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka;
Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.
出版信息
Med Educ Online. 2014 Feb 20;19:22772. doi: 10.3402/meo.v19.22772. eCollection 2014.
BACKGROUND
Individual variation of examination performance depends on many modifiable and non-modifiable factors, including pre-examination anxiety. Medical students' quality of life (QoL) and certain biochemical changes occurring while they are preparing for examinations has not been explored.
PURPOSE
We hypothesize that these parameters would determine the examination performance among medical students.
METHODS
Fourth-year medical students (n=78) from the University of Ruhuna, Sri Lanka, were invited. Their pre- and post-exam status of QoL, using the World Health Organization Quality of Life (WHOQOL-BREF) questionnaire, and the level of biochemical marker levels (i.e., serum levels of thyroid profile including thyroglobulin, cortisol and ferritin) were assessed. Differences between the scores of QoL and serum parameters were compared with their performance at the examination.
RESULTS
The mean QoL score was significantly lower at pre-exam (56.19±8.1) when compared with post-exam (61.7±7.1) levels (p<0.001). The median serum TSH level prior to the exam (0.9 mIU/L; interquartile range 0.74-1.4 mIU/L) was significantly lower (p=0.001) when compared with the level after the exam (median of 2.7 mIU/L; IQR 1.90-3.60). The mean±SD fT4 level was significantly higher before the exam (19.48±0.4 pmol/L at study entry vs. 17.43±0.3 pmol/L after the exam; p<0.001). Median serum ferritin (SF) level prior to the exam (43.15 (23.5-63.3) µg/L) was significantly lower (p≤0.001) when compared with after-exam status (72.36 (49.9-94.9) µg/L). However, there was no difference in mean serum cortisol levels (16.51±0.7 at pre-exam and 15.88±0.7 at post-exam, respectively; p=0.41).
CONCLUSIONS
Students had higher fT4 and low ferritin levels on pre-exam biochemical assessment. It was evident that students who perform better at the examination had significantly higher QoL scores at each domain tested through the questionnaire (Physical health, Psychological, Social interaction and Environment). The higher the QoL scores, the better the grades were. It was also found that students who failed exhibited profound differences in the QoL score.
背景
考试表现的个体差异取决于许多可改变和不可改变的因素，包括考前焦虑。医学生的生活质量（QoL）以及他们在备考期间发生的某些生化变化尚未得到探索。
目的
我们假设这些参数将决定医学生的考试表现。
方法
邀请来自斯里兰卡鲁胡纳大学的四年级医学生（n=78）参加。使用世界卫生组织生活质量（WHOQOL-BREF）问卷评估他们在考试前和考试后的生活质量状况以及生化标志物水平（即甲状腺球蛋白、皮质醇和铁蛋白等血清甲状腺参数水平）。比较 QoL 评分和血清参数的差异与他们在考试中的表现。
结果
与考试后（61.7±7.1）相比，考试前（56.19±8.1）的 QoL 评分显着降低（p<0.001）。考试前的中位数血清 TSH 水平（0.9 mIU/L；四分位距 0.74-1.4 mIU/L）显着降低（p=0.001），而考试后的中位数血清 TSH 水平（2.7 mIU/L；四分位距 1.90-3.60）。考试前的平均±SD fT4 水平显着升高（研究开始时为 19.48±0.4 pmol/L，考试后为 17.43±0.3 pmol/L；p<0.001）。考试前的中位数血清铁蛋白（SF）水平（43.15（23.5-63.3）µg/L）显着降低（p≤0.001），而考试后（72.36（49.9-94.9）µg/L）。然而，平均血清皮质醇水平（考试前为 16.51±0.7，考试后为 15.88±0.7）无差异（p=0.41）。
结论
学生在考前生化评估中 fT4 较高，铁蛋白较低。显然，在问卷调查中每个测试领域表现更好的学生的生活质量评分（身体健康、心理、社交互动和环境）显着更高。生活质量评分越高，成绩越好。还发现，考试不及格的学生在生活质量评分上存在显着差异。
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