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贝赫切特病表现为周围前庭病。

Behçet's disease presenting as a peripheral vestibulopathy.

机构信息

Institute of Clinical Neuroscience, Royal Prince Alfred Hospital, Central Clinical School, University of Sydney, Missenden Road, Camperdown, NSW 2050, Australia.

Healthy Hearing and Balance Care, Sydney, NSW, Australia.

出版信息

J Clin Neurosci. 2014 Jun;21(6):1060-3. doi: 10.1016/j.jocn.2013.08.021. Epub 2013 Oct 30.

DOI:10.1016/j.jocn.2013.08.021
PMID:24559656
Abstract

Prolonged acute spontaneous vertigo can be secondary to acute vestibular neuritis or posterior circulation ischaemia. We present a 66-year-old man who first developed an acute vestibular syndrome with profound unilateral hearing loss 34 years ago. First treated as vestibular neuritis, he subsequently developed manifestations of Behçet's disease, including mouth ulcers, genital ulcers and erythema nodosum over a period of 10 years. Subsequently, sudden sensorineural hearing loss affecting his only hearing ear responded to immunomodulation, confirming an autoimmune cause for the audiovestibular symptoms. This report serves as a reminder that vestibular neuritis seldom causes hearing loss; ischaemic, infective and autoimmune causes should be sought when an acute vestibular syndrome is accompanied by hearing impairment.

摘要

持续性急性自发性眩晕可能继发于急性前庭神经炎或后循环缺血。我们报告了 1 例 66 岁男性,他 34 年前首次出现急性前庭综合征,伴有单侧深度听力损失。最初被诊断为前庭神经炎,随后他出现了贝赫切特病的表现,包括口腔溃疡、生殖器溃疡和结节性红斑,持续了 10 年。随后,影响他唯一听力耳朵的突发性感音神经性听力损失对免疫调节有反应,证实了听觉前庭症状的自身免疫原因。本报告提醒我们,前庭神经炎很少引起听力损失;当急性前庭综合征伴有听力损伤时,应寻找缺血性、感染性和自身免疫性原因。

相似文献

1
Behçet's disease presenting as a peripheral vestibulopathy.贝赫切特病表现为周围前庭病。
J Clin Neurosci. 2014 Jun;21(6):1060-3. doi: 10.1016/j.jocn.2013.08.021. Epub 2013 Oct 30.
2
[Sudden deafness and Behçet's disease].
Acta Otorhinolaryngol Belg. 1989;43(3):221-9.
3
Audio-vestibular disturbances in Behcet's patients: report of 62 cases.白塞病患者的听觉-前庭功能障碍:62例报告
Hear Res. 2005 May;203(1-2):28-31. doi: 10.1016/j.heares.2004.11.020.
4
Hearing and vestibular disturbances in Behçet's syndrome.
Ann Otol Rhinol Laryngol. 1991 Jun;100(6):459-63. doi: 10.1177/000348949110000606.
5
Autoimmune sensorineural hearing loss as presenting manifestation of paediatric Behçet disease responding to adalimumab: a case report.自身免疫性感音神经性听力损失作为儿童贝赫切特病的首发表现且对阿达木单抗有反应:一例报告
Ital J Pediatr. 2016 Sep 6;42(1):81. doi: 10.1186/s13052-016-0291-2.
6
[Classification of acute vestibular syndrome].[急性前庭综合征的分类]
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2018 Jun 5;32(11):827-830. doi: 10.13201/j.issn.1001-1781.2018.11.007.
7
Difference in the nature of dizziness between vestibular neuritis and sudden sensorineural hearing loss with vertigo.前庭神经炎与伴眩晕突发性聋之间头晕性质的差异。
Otol Neurotol. 2012 Jun;33(4):623-8. doi: 10.1097/MAO.0b013e318245cc86.
8
Video head impulse test results suggest that different pathomechanisms underlie sudden sensorineural hearing loss with vertigo and vestibular neuritis: Our experience in fifty-two patients.视频头脉冲试验结果表明,伴有眩晕的突发性感音神经性听力损失和前庭神经炎存在不同的发病机制:我们对52例患者的经验。
Clin Otolaryngol. 2018 Dec;43(6):1621-1624. doi: 10.1111/coa.13196. Epub 2018 Aug 21.
9
Labyrinthine involvement in Behçet's syndrome.
J Laryngol Otol. 2001 Jul;115(7):522-9. doi: 10.1258/0022215011908315.
10
Audio-vestibular disturbance in patients with Behçet's disease.白塞病患者的听觉-前庭功能障碍
Laryngoscope. 2006 Nov;116(11):1987-90. doi: 10.1097/01.mlg.0000237442.80711.65.

引用本文的文献

1
Clinical Features and Neurotologic Findings in Patients With Acute Unilateral Peripheral Vestibulopathy Associated With Antiganglioside Antibody.抗神经节苷脂抗体相关急性单侧外周前庭病的临床特征和听力学表现
Neurology. 2023 Nov 7;101(19):e1913-e1921. doi: 10.1212/WNL.0000000000207814. Epub 2023 Sep 25.
2
Secondary autoimmune immune ear disease (AIED): a systematic review and meta-analysis on vestibular manifestations of systemic autoimmune and inflammatory disorders.继发自身免疫性内耳病 (AIED):系统性自身免疫和炎症性疾病前庭表现的系统评价和荟萃分析。
Clin Rheumatol. 2023 Oct;42(10):2747-2759. doi: 10.1007/s10067-023-06674-w. Epub 2023 Jun 28.
3
Update on Vertigo in Autoimmune Disorders, from Diagnosis to Treatment.
自身免疫性疾病性眩晕:从诊断到治疗的最新进展
J Immunol Res. 2018 Sep 26;2018:5072582. doi: 10.1155/2018/5072582. eCollection 2018.
4
Auditory involvement in Behcet's disease: relationship with demographic, clinical, and therapeutic characteristics.白塞病的听觉受累:与人口统计学、临床及治疗特征的关系
Clin Rheumatol. 2017 Feb;36(2):445-449. doi: 10.1007/s10067-016-3367-x. Epub 2016 Jul 31.