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1
Absorption of gamma benzene hexachloride following application of Kwell shampoo.
Pediatr Dermatol. 1983 Jul;1(1):74-6. doi: 10.1111/j.1525-1470.1983.tb01095.x.
2
Occupational exposure to hexachlorocyclohexane. VI. Metabolism of gamma-hexachlorocyclohexane in man.
Int Arch Occup Environ Health. 1983;52(1):59-67. doi: 10.1007/BF00380608.
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Demonstration of the percutaneous resorption of a lipophilic pesticide and its possible storage in the human body.
Arch Dermatol Res. 1982;273(1-2):43-9. doi: 10.1007/BF00509026.
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Occupational exposure to hexachlorocyclohexane. III neurophysiological findings and neuromuscular function in chronically exposed workers.
Int Arch Occup Environ Health. 1981;48(2):165-72. doi: 10.1007/BF00378437.
5
Occupational exposure to hexachlorocyclohexane. I. Body burden of HCH-isomers.
Int Arch Occup Environ Health. 1980;47(2):119-27. doi: 10.1007/BF00716371.
6
Occupational exposure to lindane: clinical and laboratory findings.职业性接触林丹：临床及实验室检查结果
Br J Ind Med. 1970 Jul;27(3):283-6. doi: 10.1136/oem.27.3.283.
7
Health surveillance and biological monitoring of pesticide formulators in India.
Toxicol Lett. 1986 Oct;33(1-3):107-14. doi: 10.1016/0378-4274(86)90075-5.
8
Serum hexachlorocyclohexane residues in workers engaged at a HCH manufacturing plant.六氯环己烷生产厂工人的血清六氯环己烷残留量
Int Arch Occup Environ Health. 1986;57(4):315-20. doi: 10.1007/BF00406186.

接触林丹的林业工人血浆中γ-六氯环己烷的浓度。

Plasma gamma-hexachlorocyclohexane concentrations in forestry workers exposed to lindane.

作者信息

Drummond L, Gillanders E M, Wilson H K

机构信息

Occupational Medicine and Hygiene Laboratory, Health and Safety Executive, London, UK.

出版信息

Br J Ind Med. 1988 Jul;45(7):493-7. doi: 10.1136/oem.45.7.493.

DOI:10.1136/oem.45.7.493
PMID:2456092
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1009635/
Abstract

Plasma gamma-hexachlorocyclohexane (gamma-HCH) and three urinary trichlorophenols were measured in forestry workers who were engaged in planting seedlings treated with gamma-HCH. These two procedures were assessed as potential biological monitoring methods and the data were compared with reported clinical symptoms. The measurement of plasma gamma-HCH was considered to be a feasible and valid monitoring method for use in routine practice and is a useful indicator of gamma-HCH absorption. The data were used to illustrate the need to be vigilant about personal hygiene and the efficacy of protective clothing. Plasma gamma-HCH concentrations above 70 nmol/l were measured in two workers which coincided with persistent non-specific clinical symptoms. Trichlorophenols were identified in urine but the extensive and variable metabolism of gamma-HCH makes this approach less suitable for biological monitoring.

摘要

对从事种植用γ-六氯环己烷处理过的幼苗的林业工人，测定了其血浆γ-六氯环己烷（γ-HCH）和三种尿中三氯酚。这两种检测方法被评估为潜在的生物监测方法，并将数据与报告的临床症状进行了比较。血浆γ-HCH的测定被认为是一种在常规实践中可行且有效的监测方法，是γ-HCH吸收的有用指标。这些数据用于说明对个人卫生保持警惕的必要性以及防护服的功效。两名工人的血浆γ-HCH浓度高于70 nmol/l，这与持续的非特异性临床症状相符。在尿液中检测到了三氯酚，但γ-HCH广泛且多变的代谢使得这种方法不太适合用于生物监测。