Cranefield P F, Aronson R S
Laboratory of Cardiac Physiology, Rockefeller University, New York, N.Y.
Pacing Clin Electrophysiol. 1988 Jun;11(6 Pt 1):670-8. doi: 10.1111/j.1540-8159.1988.tb06016.x.
The early afterdepolarization, which is an interruption of repolarization, can evoke a second upstroke or a salvo of action potentials. It is suggested that the electrophysiological characteristics of the early afterdepolarization can produce a lengthening of the QT interval and that the second upstroke and salvo of activity that may follow, it can explain many features of torsade de pointes and of certain other ventricular tachycardias. The early afterdepolarization, torsade de pointes, and repetitive monomorphic idiopathic ventricular tachycardia are all induced by bradycardia or by a preceding long RR interal. The R-on-T phenomenon is also discussed.
早期后除极是复极化的中断，可引发第二次上升支或一连串动作电位。有人提出，早期后除极的电生理特性可导致QT间期延长，其随后可能出现的第二次上升支和活动爆发可解释尖端扭转型室速和某些其他室性心动过速的许多特征。早期后除极、尖端扭转型室速和重复性单形性特发性室性心动过速均由心动过缓或之前的长RR间期诱发。文中还讨论了R波落在T波上现象。
