Division of Allergy, Asthma and Immunology, Department of Medicine, Allegheny General Hospital, Pittsburgh, Pa.
Turku Allergy Center, Turku, Finland.
J Allergy Clin Immunol Pract. 2013 May-Jun;1(3):214-26; quiz 227. doi: 10.1016/j.jaip.2013.03.012. Epub 2013 Apr 29.
Allergic rhinitis (AR) is a common pediatric problem that significantly affects sleep, learning, performance, and quality of life. In addition, it is associated with significant comorbidities and complications.
The aim was to provide an update on the epidemiology, comorbidities, pathophysiology, current treatment, and future direction of pediatric AR.
Literature reviews in each of these areas were conducted, and the results were incorporated.
The prevalence of AR is increasing in the pediatric population and is associated with significant morbidity, comorbidities, and complications. The mainstay of current treatment strategies includes allergen avoidance, pharmacotherapy, and allergen specific immunotherapy.
In the future, diagnosis will be improved by microarrayed recombinant allergen testing and therapy will be expanded to include emerging treatments such as sublingual immunotherapy and combination products.
变应性鼻炎(AR)是一种常见的儿科问题,它严重影响睡眠、学习、表现和生活质量。此外,它还与显著的合并症和并发症有关。
旨在提供变应性鼻炎儿科方面的流行病学、合并症、病理生理学、当前治疗方法和未来发展方向的最新信息。
对每个领域的文献进行了回顾,并纳入了研究结果。
AR 在儿科人群中的患病率正在增加,并与显著的发病率、合并症和并发症有关。目前治疗策略的主要方法包括过敏原回避、药物治疗和过敏原特异性免疫治疗。
未来,通过微阵列重组过敏原检测将改善诊断,治疗方法将扩大到包括新兴的治疗方法,如舌下免疫治疗和联合产品。