• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

儿童变应性鼻炎的现状与未来方向。

Current and future directions in pediatric allergic rhinitis.

机构信息

Division of Allergy, Asthma and Immunology, Department of Medicine, Allegheny General Hospital, Pittsburgh, Pa.

Turku Allergy Center, Turku, Finland.

出版信息

J Allergy Clin Immunol Pract. 2013 May-Jun;1(3):214-26; quiz 227. doi: 10.1016/j.jaip.2013.03.012. Epub 2013 Apr 29.

DOI:10.1016/j.jaip.2013.03.012
PMID:24565478
Abstract

BACKGROUND

Allergic rhinitis (AR) is a common pediatric problem that significantly affects sleep, learning, performance, and quality of life. In addition, it is associated with significant comorbidities and complications.

OBJECTIVE

The aim was to provide an update on the epidemiology, comorbidities, pathophysiology, current treatment, and future direction of pediatric AR.

METHODS

Literature reviews in each of these areas were conducted, and the results were incorporated.

RESULTS

The prevalence of AR is increasing in the pediatric population and is associated with significant morbidity, comorbidities, and complications. The mainstay of current treatment strategies includes allergen avoidance, pharmacotherapy, and allergen specific immunotherapy.

CONCLUSIONS

In the future, diagnosis will be improved by microarrayed recombinant allergen testing and therapy will be expanded to include emerging treatments such as sublingual immunotherapy and combination products.

摘要

背景

变应性鼻炎(AR)是一种常见的儿科问题,它严重影响睡眠、学习、表现和生活质量。此外,它还与显著的合并症和并发症有关。

目的

旨在提供变应性鼻炎儿科方面的流行病学、合并症、病理生理学、当前治疗方法和未来发展方向的最新信息。

方法

对每个领域的文献进行了回顾,并纳入了研究结果。

结果

AR 在儿科人群中的患病率正在增加,并与显著的发病率、合并症和并发症有关。目前治疗策略的主要方法包括过敏原回避、药物治疗和过敏原特异性免疫治疗。

结论

未来,通过微阵列重组过敏原检测将改善诊断,治疗方法将扩大到包括新兴的治疗方法,如舌下免疫治疗和联合产品。

相似文献

1
Current and future directions in pediatric allergic rhinitis.儿童变应性鼻炎的现状与未来方向。
J Allergy Clin Immunol Pract. 2013 May-Jun;1(3):214-26; quiz 227. doi: 10.1016/j.jaip.2013.03.012. Epub 2013 Apr 29.
2
[Allergic march in children, from rhinitis to asthma: management, indication of immunotherapy].[儿童过敏性进程,从鼻炎到哮喘:管理、免疫治疗指征]
Arch Pediatr. 2012 Mar;19(3):330-4. doi: 10.1016/j.arcped.2012.01.003. Epub 2012 Feb 4.
3
Chapter 15: Allergic rhinitis.第 15 章:过敏性鼻炎。
Am J Rhinol Allergy. 2013 May-Jun;27 Suppl 1:S52-5. doi: 10.2500/ajra.2013.27.3928.
4
Pharmacotherapy of allergic rhinitis: current options and future perspectives.变应性鼻炎的药物治疗:现有选择和未来展望。
Expert Opin Pharmacother. 2014 Jan;15(1):73-83. doi: 10.1517/14656566.2014.860445. Epub 2013 Nov 13.
5
Allergic rhinitis and inflammatory airway disease: interactions within the unified airspace.变应性鼻炎和炎症性气道疾病:统一气道内的相互作用。
Am J Rhinol Allergy. 2010 Jul-Aug;24(4):249-54. doi: 10.2500/ajra.2010.24.3499.
6
Pediatric allergic rhinitis: current and future state of the art.小儿过敏性鼻炎:当前与未来的技术水平
Allergy Asthma Proc. 2008 Jan-Feb;29(1):14-23. doi: 10.2500/aap2008.29.3074.
7
Analysis of comorbidities and therapeutic approach for allergic rhinitis in a pediatric population in Spain.分析西班牙儿科人群过敏性鼻炎的合并症和治疗方法。
Pediatr Allergy Immunol. 2013 Nov;24(7):678-84. doi: 10.1111/pai.12126. Epub 2013 Sep 12.
8
Emerging drugs for the treatment of perennial allergic rhinitis.治疗常年性变应性鼻炎的新兴药物
Expert Opin Emerg Drugs. 2016;21(1):57-67. doi: 10.1517/14728214.2016.1139082. Epub 2016 Jan 25.
9
Allergic rhinitis.变应性鼻炎
Mt Sinai J Med. 2011 Sep-Oct;78(5):634-44. doi: 10.1002/msj.20287.
10
[Allergic rhinitis in children].[儿童过敏性鼻炎]
Acta Med Croatica. 2011;65(2):163-8.

引用本文的文献

1
Association Between Exposure to Outdoor Artificial Light at Night and Sleep Disorders Among Children in China.夜间暴露于户外人工光与中国儿童睡眠障碍之间的关联。
JAMA Netw Open. 2022 May 2;5(5):e2213247. doi: 10.1001/jamanetworkopen.2022.13247.
2
Allergic Rhinitis: A Clinical and Pathophysiological Overview.变应性鼻炎:临床与病理生理学概述
Front Med (Lausanne). 2022 Apr 7;9:874114. doi: 10.3389/fmed.2022.874114. eCollection 2022.
3
Sublingual immunotherapy increases Treg/Th17 ratio in allergic rhinitis.舌下免疫疗法可提高变应性鼻炎患者的调节性T细胞/辅助性T细胞17比例。
Open Med (Wars). 2021 May 21;16(1):826-832. doi: 10.1515/med-2021-0285. eCollection 2021.
4
Safety of a novel intranasal formulation of azelastine hydrochloride and fluticasone propionate in children: A randomized clinical trial.新型盐酸氮卓斯汀和丙酸氟替卡松鼻内制剂在儿童中的安全性:一项随机临床试验。
Allergy Asthma Proc. 2018 Mar 1;39(2):110-116. doi: 10.2500/aap.2018.39.4116.
5
HMGB1 in the Pathogenesis of Nasal Inflammatory Diseases and its Inhibition as New Therapeutic Approach: A Review from the Literature.HMGB1在鼻炎性疾病发病机制中的作用及其抑制作为新的治疗方法:文献综述
Int Arch Otorhinolaryngol. 2017 Oct;21(4):390-398. doi: 10.1055/s-0036-1597665. Epub 2017 Jan 4.
6
Assessment of sleep disturbance in children with allergic rhinitis.变应性鼻炎患儿睡眠障碍的评估
Ann Allergy Asthma Immunol. 2017 Apr;118(4):505-506. doi: 10.1016/j.anai.2016.12.022. Epub 2017 Jan 29.
7
Early-life antibiotic use and subsequent diagnosis of food allergy and allergic diseases.早年抗生素使用与食物过敏及过敏性疾病的后续诊断
Clin Exp Allergy. 2017 Feb;47(2):236-244. doi: 10.1111/cea.12807. Epub 2016 Oct 14.
8
Longitudinal associations among asthma control, sleep problems, and health-related quality of life in children with asthma: a report from the PROMIS(®) Pediatric Asthma Study.哮喘患儿的哮喘控制、睡眠问题与健康相关生活质量之间的纵向关联:来自患者报告结果测量信息系统(PROMIS®)儿科哮喘研究的报告
Sleep Med. 2016 Apr;20:41-50. doi: 10.1016/j.sleep.2015.12.003. Epub 2016 Jan 6.
9
Administration and Burden of Subcutaneous Immunotherapy for Allergic Rhinitis in U.S. and Canadian Clinical Practice.美国和加拿大临床实践中变应性鼻炎皮下免疫治疗的管理和负担。
J Manag Care Spec Pharm. 2015 Nov;21(11):982-90. doi: 10.18553/jmcp.2015.21.11.982.
10
The perception of allergen-specific immunotherapy among pediatricians in the primary care setting.基层医疗环境中儿科医生对变应原特异性免疫疗法的认知。
Clin Mol Allergy. 2015 Jul 24;13(1):15. doi: 10.1186/s12948-015-0021-0. eCollection 2015.