Cohen Philip R
Division of Dermatology, University of California San Diego, 10991 Twinleaf Court, San Diego, CA, 92131-3643, USA,
Am J Clin Dermatol. 2014 Apr;15(2):95-100. doi: 10.1007/s40257-014-0066-8.
Basal cell carcinoma (BCC) of the axilla is rare; indeed, 70 axillary BCCs have been described in 69 patients. Using the PubMed database, an extensive literature search was performed on BCC, axilla, and axillary. Relevant papers were reviewed and the characteristics of individuals with BCC of the axilla were summarized. The calculated prevalence of axillary BCC was 0.17%. They occurred predominantly in Caucasians. The majority of patients had no obvious BCC-associated risk factors. They were observed 1.2 times more often in men than in women and twice as often in the right axilla than the left axilla. They frequently presented as an asymptomatic nodule; however, associated features have included elongation of the tumor along the axillary skin lines, ulceration, and pigmentation. The axillary tumor was typically associated with either the superficial or the nodular histologic subtype of BCC. The prognosis for these patients was usually excellent following complete removal or destruction of the tumor. In conclusion, axillary BCC is a rare clinical variant of this type of skin cancer that usually presents as an asymptomatic nodule in an individual who does not have any traditional risk factors for this malignancy. The cancer was typically associated with a non-aggressive histologic subtype. Recurrence or metastasis was uncommon following treatment of the primary tumor.
腋窝基底细胞癌（BCC）较为罕见；事实上，已报道69例患者中有70例腋窝BCC。利用PubMed数据库，对BCC、腋窝和腋部进行了广泛的文献检索。对相关论文进行了综述，并总结了腋窝BCC患者的特征。计算得出腋窝BCC的患病率为0.17%。其主要发生在白种人中。大多数患者没有明显的BCC相关危险因素。男性患者的发病率是女性的1.2倍，右侧腋窝的发病率是左侧腋窝的两倍。它们常表现为无症状结节；然而，相关特征包括肿瘤沿腋窝皮肤纹理伸长、溃疡和色素沉着。腋窝肿瘤通常与BCC的浅表或结节组织学亚型相关。在肿瘤完全切除或破坏后，这些患者的预后通常良好。总之，腋窝BCC是这种皮肤癌的一种罕见临床变体，通常表现为无任何该恶性肿瘤传统危险因素的个体的无症状结节。该癌症通常与非侵袭性组织学亚型相关。原发性肿瘤治疗后复发或转移并不常见。
