病例报告：肠内营养补充剂可能是半乳甘露聚糖检测假阳性的原因。
Case report: Enteral nutritional supplement as a likely cause of false-positive galactomannan testing.
作者信息
Ng Tong-Yong, Kang Mei-Ling, Tan Ban-Hock, Ngan Cecilia Cheng-Lai
机构信息
Department of Pathology, Singapore General Hospital, Singapore.
Department of Infectious Diseases, Singapore General Hospital, Singapore.
出版信息
Med Mycol Case Rep. 2013 Dec 16;3:11-3. doi: 10.1016/j.mmcr.2013.11.004. eCollection 2014 Jan.
Abstract
The detection of galactomannan (GM) in the serum of in immunocompromised patients is widely used for the early diagnosis of invasive aspergillosis. We report a case of a false-positive GM test presumably caused by the enteral nutritional supplement given to a non-neutropenic patient with intestinal graft-versus-host disease after a hematopoietic stem cell transplant. Clinicians should be alert to the possibility of false-positive GM results in patients on nutritional supplements.
摘要
检测免疫功能低下患者血清中的半乳甘露聚糖（GM）被广泛用于侵袭性曲霉病的早期诊断。我们报告了一例GM检测假阳性病例，推测是由于一名造血干细胞移植后患有肠道移植物抗宿主病的非中性粒细胞减少患者接受了肠内营养补充剂所致。临床医生应警惕接受营养补充剂的患者出现GM结果假阳性的可能性。
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