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生物梅里埃公司的曲霉酶免疫测定法中组织胞浆菌病相关的交叉反应性。

Histoplasmosis-associated cross-reactivity in the BioRad Platelia Aspergillus enzyme immunoassay.

作者信息

Wheat L Joseph, Hackett Emily, Durkin Michelle, Connolly Patricia, Petraitiene Ruta, Walsh Thomas J, Knox Kenneth, Hage Chadi

机构信息

MiraVista Diagnostics, 4444 Decatur Blvd., Suite 300, Indianapolis, IN 46241, USA.

出版信息

Clin Vaccine Immunol. 2007 May;14(5):638-40. doi: 10.1128/CVI.00479-06. Epub 2007 Mar 7.

DOI:10.1128/CVI.00479-06
PMID:17344352
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1865624/
Abstract

We observed false-positive results in the Platelia Aspergillus enzyme-linked immunoassay (EIA) for specimens from patients with histoplasmosis and mice with experimental infection. Platelia Aspergillus EIA-positive specimens were negative in the second-generation Histoplasma antigen EIA. Care must be taken to exclude histoplasmosis for patients with positive Platelia Aspergillus EIA results.

摘要

我们观察到，对于组织胞浆菌病患者的标本以及实验感染小鼠的标本，在曲霉胶乳凝集试验（EIA）中出现了假阳性结果。曲霉胶乳凝集试验EIA阳性的标本在第二代组织胞浆菌抗原EIA中呈阴性。对于曲霉胶乳凝集试验EIA结果呈阳性的患者，必须注意排除组织胞浆菌病。

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本文引用的文献

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Galactomannan antigen detection in the diagnosis of invasive aspergillosis.半乳甘露聚糖抗原检测在侵袭性曲霉病诊断中的应用
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Elimination of false-positive Histoplasma antigenemia caused by human anti-rabbit antibodies in the second-generation Histoplasma antigen assay.在第二代组织胞浆菌抗原检测中消除由人抗兔抗体引起的假阳性组织胞浆菌抗原血症。
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