Huff F J, Mack L, Mahlmann J, Greenberg S
Department of Psychiatry, University of Pittsburgh, PA 15213.
Brain Lang. 1988 Jul;34(2):262-78. doi: 10.1016/0093-934x(88)90138-1.
Patients with aphasia due to left hemisphere stroke and patients with Alzheimer's disease, who were matched for severity of naming impairment, were compared on tests of lexical-semantic processing. The results suggest that the lexical-semantic impairments in both groups are due to a combination of impaired access to, and loss of, lexical-semantic information, but that impaired access is more prominent in stroke patients, whereas Alzheimer's disease patients suffer a greater loss of information. The results are discussed in terms of a brain model of the storage and processing of lexical-semantic information, and with respect to implications for treatment strategies.
