Zhang Xiao-Hui, Lu Wei, Wu Qiong-Yan, Jiang Jing-Yi, Chen Dan-Qing, Qiu Li-Qian
Deparment Of Women's Health, Women's Hospital School Of Medicine Zhejiang University, No. 1 Xueshi Road, Hangzhou, Zhejiang Province, 310006, People's Republic of China.
Curr HIV Res. 2013 Dec;11(8):652-7. doi: 10.2174/1570162x12666140226102402.
This is a retrospective study based on surveillance of Human Immunodeficiency Virus type-1 (HIV-1) positive pregnant women and their children in China's Zhejiang Province. HIV counseling and testing, mother and infant characteristics, and outcomes are reported here. This study compares two principal periods, the period from 2007-2009 and the period from 2010 to 2013. The average rate of HIV counseling among pregnant women rose from 84.87% during the earlier period to 99.08% during the latter period. And the rate of HIV testing also rose significantly, from 80.60% to 98.58%. The HIV-1 prevalence among pregnant women increased slightly, from 0.01% to 0.02%. Over 70% of infected women were migrants. Half of these HIV-1 positive pregnant women were 20-30 years old. Significant differences in the characteristics of HIV-1 positive pregnant women were observed with time. The proportion of women who were employed increased dramatically from an average of 15.03% during 2007-2009 to an average of 31.34% during 2010-2013 and the proportion of women who had completed high school education increased from 0.52% to 6.51%. During 2007-2009, an average of 3.11% of these women was diagnosed before their pregnancies. During 2010-2013, this average reached to 32.53%. Sexual contact remained the primary route of transmission route during both periods, accounting for half of the infections. The proportion of women who had acquired HIV by blood transfusion declined noticeably. The proportion of mothers and children with antiretroviral therapy increased considerably over time. The overall mother-to-child transmission rate was found to be 7.14%. Although some progress has been made, further work should be performed, fostering early identification and timely therapy. Particular attention should be paid to health care of migrants.
这是一项基于对中国浙江省人类免疫缺陷病毒1型（HIV-1）阳性孕妇及其子女监测的回顾性研究。本文报告了HIV咨询与检测情况、母婴特征及结局。本研究比较了两个主要时期，即2007 - 2009年期间和2010年至2013年期间。孕妇中HIV咨询的平均比例从早期的84.87%升至后期的99.08%。HIV检测比例也显著上升，从80.60%升至98.58%。孕妇中HIV-1感染率略有上升，从0.01%升至0.02%。超过70%的感染女性为流动人口。这些HIV-1阳性孕妇中有一半年龄在20 - 30岁。随着时间推移，观察到HIV-1阳性孕妇的特征存在显著差异。就业女性比例从2007 - 2009年期间的平均15.03%大幅增至2010 - 2013年期间的平均31.34%，完成高中教育的女性比例从0.52%增至6.51%。在2007 - 2009年期间，这些女性中平均有3.11%在怀孕前被诊断出感染。在2010 - 2013年期间，这一平均比例达到32.53%。两个时期性接触均为主要传播途径，占感染病例的一半。通过输血感染HIV的女性比例明显下降。接受抗逆转录病毒治疗的母婴比例随时间大幅增加。总体母婴传播率为7.14%。尽管已取得一些进展，但仍应开展进一步工作，促进早期识别和及时治疗。应特别关注流动人口的医疗保健。
