Department of Respirology, Ehime Prefectural Central Hospital, Japan.
Department of Neurology, Ehime Prefectural Central Hospital, Japan.
Intern Med. 2021 Dec 15;60(24):3953-3956. doi: 10.2169/internalmedicine.7426-21. Epub 2021 Jun 12.
A 23-year-old woman was transferred to our hospital due to exacerbating dyspnea with wheeze. After admission, we started mechanical ventilation immediately, and she was diagnosed with status asthmatics. On the following day, she was able to be weaned from the ventilator. However, she required re-intubation because of an unstable respiratory condition just after extubation. Detailed neurological investigations identified blepharoptosis and muscle weakness with easy fatigability. An edrophonium test was positive. Anti-acetylcholine receptor antibody was detected in her serum. She was finally diagnosed with myasthenia gravis and successfully treated with neostigmine and a low-dose corticosteroid.
一位 23 岁女性因哮喘加重伴呼吸困难转入我院。入院后，我们立即开始进行机械通气，诊断为哮喘持续状态。次日，患者成功脱机。但在拔管后，由于呼吸状况不稳定，患者再次插管。详细的神经学检查发现眼睑下垂和肌肉无力，且易疲劳。腾喜龙试验阳性，血清中乙酰胆碱受体抗体检测阳性。最终诊断为重症肌无力，经新斯的明和小剂量皮质类固醇治疗后成功治愈。
