WINROP 可改变 ROP 筛查实践：在松兹瓦尔省和西曼兰省人群中对 WINROP 的验证。
WINROP can modify ROP screening praxis: a validation of WINROP in populations in Sörmland and Västmanland.
机构信息
Ophthalmology Department, Västmanland Hospital in Västerås, Västerås, Sweden.
Ophthalmology Department, Mälarsjukhuset in Eskilstuna, Eskilstuna, Sweden.
出版信息
Br J Ophthalmol. 2014 Jul;98(7):964-6. doi: 10.1136/bjophthalmol-2013-304617. Epub 2014 Feb 25.
BACKGROUND
This study validates the newly developed WINROP algorithm aimed at detecting retinopathy of prematurity (ROP) requiring treatment at an early stage. The study was conducted at two middle-sized hospitals in Sweden, prospectively and retrospectively.
METHODS
A total of 104 children participated in this study. Their mean gestational age at birth was 28.7 weeks (range, 23.6-32.1 weeks), and their mean birth weight was 1208 g (range, 477-2340 g). Weekly weight measurements were used in WINROP to calculate the risk of developing ROP.
RESULTS
80% of infants (83/104) had no ROP, 15% (16/104) had mild ROP (stage 1 or 2), 5% (5/104) had severe ROP, and 2% (2/104) were treated for ROP. The alarm was registered at an average of 2 weeks postnatal age (range 1-6 weeks).
CONCLUSIONS
WINROP identified all the infants at risk for developing stage 3 ROP (100% sensitivity) and had a 59% specificity. The alarm was registered several weeks before screening for ROP began. WINROP can be used to complement conventional ROP screening.
背景
本研究验证了新开发的 WINROP 算法，旨在早期发现需要治疗的早产儿视网膜病变（ROP）。该研究在瑞典的两家中型医院进行，前瞻性和回顾性。
方法
共有 104 名儿童参与了这项研究。他们的平均出生胎龄为 28.7 周（范围 23.6-32.1 周），平均出生体重为 1208 克（范围 477-2340 克）。WINROP 中使用每周体重测量来计算发生 ROP 的风险。
结果
80%的婴儿（83/104）没有 ROP，15%（16/104）有轻度 ROP（1 期或 2 期），5%（5/104）有严重 ROP，2%（2/104）需要治疗 ROP。报警平均在出生后 2 周（范围 1-6 周）时登记。
结论
WINROP 识别出所有有发展为 3 期 ROP 风险的婴儿（100%的敏感性），特异性为 59%。警报在开始 ROP 筛查前几周发出。WINROP 可用于补充常规 ROP 筛查。
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