Shah Parag K, Prabhu Vishma, Karandikar Smita S, Ranjan Ratnesh, Narendran Venkatapathy, Kalpana Narendran
Parag K Shah, Vishma Prabhu, Smita S Karandikar, Ratnesh Ranjan, Venkatapathy Narendran, Narendran Kalpana, Pediatric Retina and Ocular Oncology Department, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Coimbatore 641014, Tamilnadu, India.
World J Clin Pediatr. 2016 Feb 8;5(1):35-46. doi: 10.5409/wjcp.v5.i1.35.
Retinopathy of prematurity (ROP) is a vasoproliferative disorder of the retina occurring principally in new born preterm infants. It is an avoidable cause of childhood blindness. With the increase in the survival of preterm babies, ROP has become the leading cause of preventable childhood blindness throughout the world. A simple screening test done within a few weeks after birth by an ophthalmologist can avoid this preventable blindness. Although screening guidelines and protocols are strictly followed in the developed nations, it lacks in developing economies like India and China, which have the highest number of preterm deliveries in the world. The burden of this blindness in these countries is set to increase tremendously in the future, if corrective steps are not taken immediately. ROP first emerged in 1940s and 1950s, when it was called retrolental fibroplasia. Several epidemics of this disease were and are still occurring in different regions of the world and since then a lot of research has been done on this disease. However, till date very few comprehensive review articles covering all the aspects of ROP are published. This review highlights the past, present and future strategies in managing this disease. It would help the pediatricians to update their current knowledge on ROP.
早产儿视网膜病变（ROP）是一种主要发生于早产新生儿的视网膜血管增生性疾病。它是儿童失明的一个可避免病因。随着早产婴儿存活率的提高，ROP已成为全球可预防儿童失明的首要原因。出生后几周内由眼科医生进行的一项简单筛查测试可避免这种可预防的失明。尽管发达国家严格遵循筛查指南和方案，但在印度和中国等发展中经济体却缺乏相关措施，而这两个国家的早产分娩数量位居世界之首。如果不立即采取纠正措施，未来这些国家这种失明的负担将大幅增加。ROP最早出现在20世纪40年代和50年代，当时被称为晶状体后纤维增生症。这种疾病的几次流行过去和现在都在世界不同地区发生，从那时起针对这种疾病已经开展了大量研究。然而，迄今为止，很少有涵盖ROP所有方面的全面综述文章发表。本综述重点介绍了管理这种疾病的过去、现在和未来策略。它将有助于儿科医生更新他们目前关于ROP的知识。
