浆细胞样骨髓瘤在一名年轻成人中表现为快速进展性肾衰竭。
Plasmablastic myeloma presenting as rapidly progressive renal failure in a young adult.
作者信息
Srija M, Zachariah P P, Unni V N, Mathew A, Rajesh R, Kurian G, Neeraj S, Seethalekshmi N V, Smitha N V
机构信息
Department of Nephrology, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.
Department of Hematology and Stem Cell Transplantation Unit, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.
出版信息
Indian J Nephrol. 2014 Jan;24(1):41-4. doi: 10.4103/0971-4065.125081.
Multiple myeloma (MM) is a condition where there is malignant proliferation of plasma cells. There is a strong correlation with age, peaking at 60-70 years. The clinical course in adolescents and young individuals is generally indolent and the survival is longer. We report a case of a 28-year-old male, who was diagnosed to have plasmablastic myeloma, an atypical variant of MM with a poor prognosis, presenting as rapidly progressive renal failure. He was given induction chemotherapy and then underwent autologous peripheral blood stem cell transplantation.
多发性骨髓瘤（MM）是一种浆细胞恶性增殖的疾病。它与年龄有很强的相关性，发病高峰在60至70岁。青少年和年轻人的临床病程通常较为惰性，生存期较长。我们报告一例28岁男性病例，该患者被诊断为浆母细胞性骨髓瘤，这是MM的一种非典型变体，预后较差，表现为快速进展的肾衰竭。他接受了诱导化疗，然后进行了自体外周血干细胞移植。
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