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肺癌患者血栓栓塞事件的发生率及预测因素

The incidence and predictors of thromboembolic events in patients with lung cancer.

作者信息

Kadlec Bohdan, Skrickova Jana, Merta Zdenek, Dusek Ladislav, Jarkovsky Jiri

机构信息

Department of Respiratory Diseases and TB, Faculty of Medicine, Masaryk University and University Hospital, Brno, Czech Republic.

Institute of Biostatistics and Analyses, Faculty of Medicine and Faculty of Science, Masaryk University, Brno, Czech Republic.

出版信息

ScientificWorldJournal. 2014 Jan 20;2014:125706. doi: 10.1155/2014/125706. eCollection 2014.

Abstract

Patients with lung cancer experience elevated risk of venous thromboembolism. Cancer patients with thrombosis have a shorter life expectancy and the occurrence of VTE worsens the quality of life and may delay, interrupt, or completely halt the cancer therapy. In a large cohort of lung cancer patients we monitored the incidence of venous thromboembolism and we identified groups of patients with the highest risk of venous thromboembolism suitable for antithrombotic prophylaxis, which could favourably affect their morbidity and mortality.

摘要

肺癌患者发生静脉血栓栓塞的风险升高。患有血栓形成的癌症患者预期寿命较短,静脉血栓栓塞症(VTE)的发生会使生活质量恶化,并可能延迟、中断或完全停止癌症治疗。在一大群肺癌患者中,我们监测了静脉血栓栓塞的发生率,并确定了适合进行抗血栓预防的、静脉血栓栓塞风险最高的患者群体,这可能会对他们的发病率和死亡率产生有利影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3ce/3918375/71eec2b0b1ab/TSWJ2014-125706.001.jpg

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